Name

IRAK3 Gene

interleukin-1 receptor-associated kinase 3

This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

IRAK3 PROTAC 23 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the IRAK3 PROTAC 23 drug from theDGIdb Drug Targets 2026 dataset.

IRAK1-IRAK3 complex Gene Set

From CORUM Protein Complexes

proteins in the IRAK1-IRAK3 complex protein complex from the CORUM Protein Complexes dataset.

irak3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term irak3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

IRAK3 Gene Set

From KEA Substrates of Kinases

substrates of the kinase IRAK3 from the curated KEA Substrates of Kinases dataset.

IRAK3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for IRAK3 from the Pathway Commons Protein-Protein Interactions dataset.

IRAK3 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the IRAK3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

BCL6 PROTAC 15 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the BCL6 PROTAC 15 drug from theDGIdb Drug Targets 2026 dataset.

BCL6 PROTAC A19 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the BCL6 PROTAC A19 drug from theDGIdb Drug Targets 2026 dataset.

PROTAC 23 [PMID: 38321747] Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the PROTAC 23 [PMID: 38321747] drug from theDGIdb Drug Targets 2026 dataset.

CDK9 PROTAC C3 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the CDK9 PROTAC C3 drug from theDGIdb Drug Targets 2026 dataset.

SOS1 PROTAC 9D Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the SOS1 PROTAC 9D drug from theDGIdb Drug Targets 2026 dataset.

TBK1 PROTAC 3I Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the TBK1 PROTAC 3I drug from theDGIdb Drug Targets 2026 dataset.