Harmonizome 3.0

LIM domain only 2 (rhombotin-like 1)

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the LMO2-20887958-HPC-7-MOUSE transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

From ChEA Transcription Factor Targets 2022

target genes of the LMO2-20887958-HPC-7-MOUSE transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

From ChEA Transcription Factor Targets

target genes of the LMO2 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

From CORUM Protein Complexes

proteins in the Gata1-Tal1-Tcf3-Lmo2 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Rb-tal-1-E2A-Lmo2-Ldb1 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Ldb1-Lmo2-Gata-1-Tal1-E47 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Gata2-Tal1-Tcf3-Lmo2 complex protein complex from the CORUM Protein Complexes dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lmo2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From MotifMap Predicted Transcription Factor Targets

target genes of the Lmo2 complex transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for LMO2 from the Pathway Commons Protein-Protein Interactions dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC8321895-41375_2020_779_MOESM4_ESM.xlsx-marker_genes-LMO2-LYL1_LYL1 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the LMO2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.