Harmonizome 3.0

mutated in colorectal cancers

This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical MCC-257 from the curated CTD Gene-Chemical Interactions dataset.

From CORUM Protein Complexes

proteins in the Mitotic checkpoint complex (MCC) protein complex from the CORUM Protein Complexes dataset.

From DrugBank Drug Targets

interacting proteins for the MCC drug from the curated DrugBank Drug Targets dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mcc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein MCC from the curated Hub Proteins Protein-Protein Interactions dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for MCC from the Pathway Commons Protein-Protein Interactions dataset.