Name

MELK Gene

maternal embryonic leucine zipper kinase

Enables calcium ion binding activity; non-membrane spanning protein tyrosine kinase activity; and protein serine/threonine kinase activity. Involved in apoptotic process; cell population proliferation; and protein autophosphorylation. Located in cell cortex and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

melk Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term melk in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MELK Gene Set

From KEA Substrates of Kinases

substrates of the kinase MELK from the curated KEA Substrates of Kinases dataset.

MELK Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MELK from the Pathway Commons Protein-Protein Interactions dataset.

MELK Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase MELK from the curated PhosphoSitePlus Substrates of Kinases dataset.

MELK Gene Set

From Kinase Library Serine Threonine Kinome Atlas

substrates of the kinase MELK from the Kinase Library Serine Threonine Kinome Atlas dataset.

MELK Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the MELK gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

MELK Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the MELK gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

MELK-TI Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the MELK-TI drug from theDGIdb Drug Targets 2026 dataset.

MELK INHIBITOR OTS167 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the MELK INHIBITOR OTS167 drug from theDGIdb Drug Targets 2026 dataset.