Name

MMP11 Gene

matrix metallopeptidase 11

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]

mmp11 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mmp11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MMP11 Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for MMP11 from the MSigDB Cancer Gene Co-expression Modules dataset.

MMP11 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MMP11 from the Pathway Commons Protein-Protein Interactions dataset.

mmp1112 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mmp1112 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mmp11607 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mmp11607 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mmp11607dupg Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mmp11607dupg in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mmp11607gg Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mmp11607gg in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mmp11067 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mmp11067 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.