Name

MOGS Gene

mannosyl-oligosaccharide glucosidase

This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

MOGS Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MOGS from the Pathway Commons Protein-Protein Interactions dataset.

MOGS Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the MOGS gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

Defective MOGS causes MOGS-CDG (CDG-2b) Gene Set

From Reactome Pathways 2014

proteins participating in the Defective MOGS causes MOGS-CDG (CDG-2b) pathway from the Reactome Pathways dataset.

Defective MOGS causes CDG-2b Gene Set

From Reactome Pathways 2024

proteins participating in the Defective MOGS causes CDG-2b pathway from the Reactome Pathways 2024 dataset.

MOGS-congenital disorder of glycosylation Gene Set

From ClinVar Gene-Phenotype Associations 2025

genes associated with the MOGS-congenital disorder of glycosylation phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.