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PALB2 Genepartner and localizer of BRCA2 This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008] |
palb2 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term palb2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
PALB2 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for PALB2 from the Pathway Commons Protein-Protein Interactions dataset. |
PALB2 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PALB2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
BL3800 (PALB2) Gene Setproteins in the BL3800 (PALB2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Gene Setproteins participating in the Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function pathway from the Reactome Pathways 2024 dataset. |
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function Gene Setproteins participating in the Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function pathway from the Reactome Pathways 2024 dataset. |
Defective homologous recombination repair (HRR) due to PALB2 loss of function Gene Setproteins participating in the Defective homologous recombination repair (HRR) due to PALB2 loss of function pathway from the Reactome Pathways 2024 dataset. |
Impaired BRCA2 binding to PALB2 Gene Setproteins participating in the Impaired BRCA2 binding to PALB2 pathway from the Reactome Pathways 2024 dataset. |
PALB2-related cancer predisposition Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the PALB2-related cancer predisposition phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |