Name

PALB2 Gene

partner and localizer of BRCA2

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008]

palb2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term palb2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PALB2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PALB2 from the Pathway Commons Protein-Protein Interactions dataset.

PALB2 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the PALB2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

BL3800 (PALB2) Gene Set

From NURSA Protein Complexes

proteins in the BL3800 (PALB2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Gene Set

From Reactome Pathways 2024

proteins participating in the Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function pathway from the Reactome Pathways 2024 dataset.

Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function Gene Set

From Reactome Pathways 2024

proteins participating in the Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function pathway from the Reactome Pathways 2024 dataset.

Defective homologous recombination repair (HRR) due to PALB2 loss of function Gene Set

From Reactome Pathways 2024

proteins participating in the Defective homologous recombination repair (HRR) due to PALB2 loss of function pathway from the Reactome Pathways 2024 dataset.

Impaired BRCA2 binding to PALB2 Gene Set

From Reactome Pathways 2024

proteins participating in the Impaired BRCA2 binding to PALB2 pathway from the Reactome Pathways 2024 dataset.

PALB2-related cancer predisposition Gene Set

From ClinVar Gene-Phenotype Associations 2025

genes associated with the PALB2-related cancer predisposition phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.