PLCG1

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Results for "PLCG1": 2 genes, 12 gene sets

Name
PLCG1 Gene phospholipase C, gamma 1 The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PLCG1-AS1 Gene PLCG1 antisense RNA 1
plcg1 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term plcg1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
PLCG1 Gene Set From Hub Proteins Protein-Protein Interactions interacting proteins for hub protein PLCG1 from the curated Hub Proteins Protein-Protein Interactions dataset.
PLCG1 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for PLCG1 from the Pathway Commons Protein-Protein Interactions dataset.
PLCG1 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the PLCG1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
PLCG1 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PLCG1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
PLCG1 events in ERBB2 signaling Gene Set From Reactome Pathways 2014 proteins participating in the PLCG1 events in ERBB2 signaling pathway from the Reactome Pathways dataset.
Human - Motor Cortex - Cluster - FGFR3+ PLCG1+ Layer 1-6 astrocyte Gene Set From HuBMAP Azimuth Cell Type Annotations genes associated with the Human - Motor Cortex - Cluster - FGFR3+ PLCG1+ Layer 1-6 astrocyte cell type from the HuBMAP Azimuth Cell Type Annotations dataset.
Activated NTRK2 signals through PLCG1 Gene Set From Reactome Pathways 2024 proteins participating in the Activated NTRK2 signals through PLCG1 pathway from the Reactome Pathways 2024 dataset.
Activated NTRK3 signals through PLCG1 Gene Set From Reactome Pathways 2024 proteins participating in the Activated NTRK3 signals through PLCG1 pathway from the Reactome Pathways 2024 dataset.
PLCG1 events in ERBB2 signaling Gene Set From Reactome Pathways 2024 proteins participating in the PLCG1 events in ERBB2 signaling pathway from the Reactome Pathways 2024 dataset.
Brain_CT2_Astro L1-6 FGFR3 PLCG1 Gene Set From HuBMAP ASCT+B Annotations biomarker genes for the Brain_CT2_Astro L1-6 FGFR3 PLCG1 cell type from the HuBMAP ASCT+B dataset.
Brain_CT2_Astro L1-6 FGFR3 PLCG1 Gene Set From HuBMAP ASCT+B Augmented with RNA-seq Coexpression biomarker genes for the Brain_CT2_Astro L1-6 FGFR3 PLCG1 cell type from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset.