PORCN

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Results for "PORCN": 1 gene, 5 gene sets

Name
PORCN Gene porcupine homolog (Drosophila) This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2013]
PORCN Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for PORCN from the Pathway Commons Protein-Protein Interactions dataset.
PORCN Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the PORCN gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
PORCN Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PORCN gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 Gene Set From Reactome Pathways 2014 proteins participating in the WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 pathway from the Reactome Pathways dataset.
LGK974 inhibits PORCN Gene Set From Reactome Pathways 2024 proteins participating in the LGK974 inhibits PORCN pathway from the Reactome Pathways 2024 dataset.