| Name |
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RUNX3 Generunt-related transcription factor 3 This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
RUNX3 Gene SetFrom ENCODE Transcription Factor Targets target genes of the RUNX3 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. |
runx3 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term runx3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
RUNX3 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for RUNX3 from the Pathway Commons Protein-Protein Interactions dataset. |
RUNX3 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the RUNX3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
RUNX3 Gene SetFrom JASPAR Predicted Human Transcription Factor Targets 2025 target genes of the RUNX3 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. |
RUNX3 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the RUNX3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
RUNX3 Regulates Immune Response and Cell Migration Gene Setproteins participating in the RUNX3 Regulates Immune Response and Cell Migration pathway from the Reactome Pathways 2024 dataset. |
RUNX3 regulates BCL2L11 (BIM) transcription Gene Setproteins participating in the RUNX3 regulates BCL2L11 (BIM) transcription pathway from the Reactome Pathways 2024 dataset. |
RUNX3 regulates CDKN1A transcription Gene Setproteins participating in the RUNX3 regulates CDKN1A transcription pathway from the Reactome Pathways 2024 dataset. |
RUNX3 regulates NOTCH signaling Gene Setproteins participating in the RUNX3 regulates NOTCH signaling pathway from the Reactome Pathways 2024 dataset. |
RUNX3 regulates RUNX1-mediated transcription Gene Setproteins participating in the RUNX3 regulates RUNX1-mediated transcription pathway from the Reactome Pathways 2024 dataset. |
RUNX3 regulates WNT signaling Gene Setproteins participating in the RUNX3 regulates WNT signaling pathway from the Reactome Pathways 2024 dataset. |
RUNX3 regulates YAP1-mediated transcription Gene Setproteins participating in the RUNX3 regulates YAP1-mediated transcription pathway from the Reactome Pathways 2024 dataset. |
RUNX3 regulates p14-ARF Gene Setproteins participating in the RUNX3 regulates p14-ARF pathway from the Reactome Pathways 2024 dataset. |
Regulation of RUNX3 expression and activity Gene Setproteins participating in the Regulation of RUNX3 expression and activity pathway from the Reactome Pathways 2024 dataset. |
Transcriptional regulation by RUNX3 Gene Setproteins participating in the Transcriptional regulation by RUNX3 pathway from the Reactome Pathways 2024 dataset. |