Harmonizome 3.0

From ESCAPE

Sets of target genes of transcription factors from published ChIP-chip, ChIP-seq, and other transcription factor binding site profiling studies;sets of differentially expressed genes following perturbation of a protein from gene expression data in GEO; sets of interacting proteins from high- and low-throughput protein-protein interaction studies; sets of targets of microRNAs from public databases, computationally predicted or experimentally verified

From Hub Proteins

Sets of proteins interacting with hub proteins aggregated from data

From SILAC Phosphoproteomics

Phosphorylation levels of proteins in cell lines following drug treatment

From SILAC Phosphoproteomics

Phosphorylation levels of proteins in cell lines following genetic perturbation (knockdown, knockout, over-expression, mutation)

From SILAC Phosphoproteomics

Phosphorylation levels of proteins in cell lines following ligand treatment

From GlyGen

Proteins glycosylated by saccharide ligands from glycosylation site citations

From ChIP-X Enrichment Analysis

Target genes of transcription factors from published ChIP-chip, ChIP-seq, and other transcription factor binding site profiling studies

From DrugBank

Sets of proteins targeted by drugs by manual literature curation

From Encyclopedia of DNA Elements

Target genes of transcription factors from transcription factor binding site profiles

From Jaspar PWMs

Target genes of transcription factors predicted using known transcription factor binding site motifs

From LINCS KinomeScan

Kinase inhibitor targets from percent inhibition of kinases by small molecules measured using purified kinases

From MiRTarBase

Target genes of microRNAs from published experiments

From MotifMap

Target genes of transcription factors predicted using known transcription factor binding site motifs

From TargetScan

Target genes of microRNAs predicted by searching genes for sites matching conserved miRNA seed regions

From TargetScan

Target genes of microRNAs predicted by searching genes for sites matching nonconserved miRNA seed regions

From ChIP-X Enrichment Analysis

Target genes of transcription factors from published ChIP-chip, ChIP-seq, and other transcription factor binding site profiling studies

From Jaspar PWMs

Target genes of human transcription factors predicted using known transcription factor binding site motifs

From Jaspar PWMs

Target genes of mouse transcription factors predicted using known transcription factor binding site motifs

From Drug-Gene Interaction Database

Sets of proteins targeted by drugs by data aggregation