TDG

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Results for "TDG": 1 gene, 7 gene sets

Name
TDG Gene thymine-DNA glycosylase The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
tdg Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term tdg in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
TDG Gene Set From MSigDB Cancer Gene Co-expression Modules co-expressed genes for TDG from the MSigDB Cancer Gene Co-expression Modules dataset.
TDG Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for TDG from the Pathway Commons Protein-Protein Interactions dataset.
TDG Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the TDG gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
TDG Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the TDG gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
TET1,2,3 and TDG demethylate DNA Gene Set From Reactome Pathways 2014 proteins participating in the TET1,2,3 and TDG demethylate DNA pathway from the Reactome Pathways dataset.
TET1,2,3 and TDG demethylate DNA Gene Set From Reactome Pathways 2024 proteins participating in the TET1,2,3 and TDG demethylate DNA pathway from the Reactome Pathways 2024 dataset.