Harmonizome 3.0

valyl-tRNA synthetase 2, mitochondrial

This gene encodes a mitochondrial aminoacyl-tRNA synthetase, which catalyzes the attachment of valine to tRNA(Val) for mitochondrial translation. Mutations in this gene cause combined oxidative phosphorylation deficiency-20, and are also associated with early-onset mitochondrial encephalopathies. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2014]

valyl-tRNA synthetase

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]

valyl-tRNA synthetase 1

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical valyl-prolyl-aspartyl-prolyl-arginine from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical benzyloxycarbonyl-valyl-alanyl-aspartic acid from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical tyrosyl-valyl-alanyl-aspartal from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical benzyloxycarbonyl-alanyl-glutamyl-valyl-aspartic acid fluoromethyl ketone from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical N-benzyloxycarbonyl-valyl-leucyl-leucinal from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical deuterohemin-alanyl-histidyl-threonyl-valyl-glutamyl-lysine from the curated CTD Gene-Chemical Interactions dataset.

From GO Biological Process Annotations 2015

genes participating in the valyl-trna aminoacylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From DeepCoverMOA Drug Mechanisms of Action

proteins with high or low expression in L-Valyl-L-phenylalanine relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.

From GO Biological Process Annotations 2023

genes participating in the valyl-tRNA aminoacylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2025

genes participating in the valyl-tRNA aminoacylation biological process from the curated GO Biological Process Annotations 2025 dataset.