Name

BMF Gene

Bcl2 modifying factor

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

bmf Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term bmf in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BMF Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for BMF from the Pathway Commons Protein-Protein Interactions dataset.

BMF Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the BMF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

BMF Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the BMF gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

Activation of BMF and translocation to mitochondria Gene Set

From Reactome Pathways 2014

proteins participating in the Activation of BMF and translocation to mitochondria pathway from the Reactome Pathways dataset.

Activation of BMF and translocation to mitochondria Gene Set

From Reactome Pathways 2024

proteins participating in the Activation of BMF and translocation to mitochondria pathway from the Reactome Pathways 2024 dataset.

FLT3 INHIBITOR BMF-500 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3 INHIBITOR BMF-500 drug from theDGIdb Drug Targets 2026 dataset.