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CAT Genecatalase This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009] |
cat Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term cat in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
CAT Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for CAT from the Pathway Commons Protein-Protein Interactions dataset. |
CAT Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the CAT gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
CAT Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the CAT gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
cat-scratch disease Gene SetFrom DISEASES Text-mining Gene-Disease Association Evidence Scores genes co-occuring with the disease cat-scratch disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset. |
CAT-213 Gene Setinteracting proteins for the CAT-213 drug from the curated DrugBank Drug Targets dataset. |
Cat eye syndrome critical region protein 6 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Cat eye syndrome critical region protein 6 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Cat eye syndrome critical region protein 2 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Cat eye syndrome critical region protein 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Cat eye syndrome critical region protein 5 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Cat eye syndrome critical region protein 5 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
cat eye syndrome Gene SetFrom OMIM Gene-Disease Associations genes associated with the cat eye syndrome phenotype from the curated OMIM Gene-Disease Associations dataset. |
Cat Eye Syndrome Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Cat Eye Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
Cat-Scratch Disease Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Cat-Scratch Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
CAT tailing Gene SetFrom GO Biological Process Annotations 2023 genes participating in the CAT tailing biological process from the curated GO Biological Process Annotations 2023 dataset. |
CAT tailing Gene SetFrom GO Biological Process Annotations 2025 genes participating in the CAT tailing biological process from the curated GO Biological Process Annotations 2025 dataset. |
cat-scratch disease Gene SetFrom DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 genes co-occuring with the disease cat-scratch disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. |