CTLA4

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Results for "CTLA4": 1 gene, 10 gene sets

Name
CTLA4 Gene cytotoxic T-lymphocyte-associated protein 4 This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
ctla4 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term ctla4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
CTLA4 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for CTLA4 from the Pathway Commons Protein-Protein Interactions dataset.
CTLA4 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the CTLA4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
ctla4 cd28 haplotypes Gene Set From GAD Gene-Disease Associations genes associated with the disease ctla4 cd28 haplotypes in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
CTLA4 inhibitory signaling Gene Set From Reactome Pathways 2014 proteins participating in the CTLA4 inhibitory signaling pathway from the Reactome Pathways dataset.
Ctla4 Deficiency Gene Set From DisGeNET Gene-Disease Associations genes associated with the disease Ctla4 Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
Ctla4 Haploinsufficiency Gene Set From DisGeNET Gene-Disease Associations genes associated with the disease Ctla4 Haploinsufficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
Cancer immunotherapy by CTLA4 blockade Gene Set From WikiPathways Pathways 2024 proteins participating in the Cancer immunotherapy by CTLA4 blockade pathway from the WikiPathways Pathways 2024 dataset.
CTLA4 inhibitory signaling Gene Set From Reactome Pathways 2024 proteins participating in the CTLA4 inhibitory signaling pathway from the Reactome Pathways 2024 dataset.
Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency Gene Set From ClinVar Gene-Phenotype Associations 2025 genes associated with the Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.