Name

CXCR1 Gene

chemokine (C-X-C motif) receptor 1

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]

cxcr1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cxcr1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CXCR1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CXCR1 from the Pathway Commons Protein-Protein Interactions dataset.

CXCR1 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the CXCR1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

IL8- and CXCR1-mediated signaling events Gene Set

From PID Pathways

proteins participating in the IL8- and CXCR1-mediated signaling events pathway from the PID Pathways dataset.

CXCR1 chemokine receptor binding Gene Set

From GO Molecular Function Annotations 2023

genes performing the CXCR1 chemokine receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

CXCR1 chemokine receptor binding Gene Set

From GO Molecular Function Annotations 2025

genes performing the CXCR1 chemokine receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.