Name

DCC Gene

DCC netrin 1 receptor

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]

LOC343052 Gene

immunoglobulin superfamily, DCC subclass, member 3 pseudogene

IGDCC3 Gene

immunoglobulin superfamily, DCC subclass, member 3

Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within neuromuscular process controlling balance. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

IGDCC4 Gene

immunoglobulin superfamily, DCC subclass, member 4

Predicted to be involved in cell-cell adhesion. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

LOC105371448 Gene

immunoglobulin superfamily DCC subclass member 3-like

LOC100631370 Gene

immunoglobulin superfamily, DCC subclass, member 3 pseudogene

DCC-2036_Ramos (RA 1) Gene Set

From LINCS Kinativ Kinase Inhibitor Bioactivity Profiles

kinases with high inhibition of kinase activity in the DCC-2036_Ramos (RA 1) chemical bioactivity profile from the Kinativ Kinase Inhibitor Bioactivity Profiles dataset.

dcc Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dcc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

DCC Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for DCC from the MSigDB Cancer Gene Co-expression Modules dataset.

DCC Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DCC from the Pathway Commons Protein-Protein Interactions dataset.

Role of DCC in regulating apoptosis Gene Set

From Reactome Pathways 2014

proteins participating in the Role of DCC in regulating apoptosis pathway from the Reactome Pathways dataset.

DCC mediated attractive signaling Gene Set

From Reactome Pathways 2014

proteins participating in the DCC mediated attractive signaling pathway from the Reactome Pathways dataset.

DCC mediated attractive signaling Gene Set

From Reactome Pathways 2024

proteins participating in the DCC mediated attractive signaling pathway from the Reactome Pathways 2024 dataset.

RAF INHIBITOR DCC-3084 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the RAF INHIBITOR DCC-3084 drug from theDGIdb Drug Targets 2026 dataset.

KIT-MUTANT INHIBITOR DCC-3009 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the KIT-MUTANT INHIBITOR DCC-3009 drug from theDGIdb Drug Targets 2026 dataset.