Name

DrugBank Drug Targets Dataset

From DrugBank

Sets of proteins targeted by drugs by manual literature curation

DeepCoverMOA Drug Mechanisms of Action Dataset

From DeepCoverMOA

Protein expression profiles in HCT116 cell line following drug treatment

RummaGEO Drug Perturbation Signatures Dataset

From RummaGEO

Drug perturbation signatures produced from automatically mined RNA-seq samples from GEO.

NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles Dataset

From Novartis Institutes for Biomedical Research

Drug perturbation signatures created by profiling 4343 small molecules in the U2-OS cell line with the DRUG-seq platform

Sci-Plex Drug Perturbation Signatures Dataset

From Sci-Plex

sciRNA-seq expression profiles for A549, K562, and MCF7 cells treated with 188 compounds at 4 doses

DGIdb Drug Targets 2026 Dataset

From Drug-Gene Interaction Database

Sets of proteins targeted by drugs by data aggregation

BioGPS Human Cell Type and Tissue Gene Expression Profiles Dataset

From BioGPS

mRNA expression profiles for human tissues and cell types

BioGPS Mouse Cell Type and Tissue Gene Expression Profiles Dataset

From BioGPS

mRNA expression profiles for mouse tissues and cell types

ESCAPE Omics Signatures of Genes and Proteins for Stem Cells Dataset

From ESCAPE

Sets of target genes of transcription factors from published ChIP-chip, ChIP-seq, and other transcription factor binding site profiling studies;sets of differentially expressed genes following perturbation of a protein from gene expression data in GEO; sets of interacting proteins from high- and low-throughput protein-protein interaction studies; sets of targets of microRNAs from public databases, computationally predicted or experimentally verified

HPM Cell Type and Tissue Protein Expression Profiles Dataset

From Human Proteome Map

Protein expression profiles for tissues and cell types

ProteomicsDB Cell Type and Tissue Protein Expression Profiles Dataset

From Proteomics Database

Protein expression profiles for tissues and cell types reprocessed from many proteomics datasets

Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles Dataset

From Roadmap Epigenomics

DNA methylation profiles for primary cell types and tissues

Roadmap Epigenomics Cell and Tissue Gene Expression Profiles Dataset

From Roadmap Epigenomics

mRNA expression profiles for primary cell types and tissues

Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles Dataset

From Allen Brain Atlas

mRNA expression profiles for dementia and traumatic brain injuries (TBI) from aging brain tissue

dbGAP Gene-Trait Associations Dataset

From Database of Genotypes and Phenotypes

Gene-trait associations curated from genetic association studies

GDSC Cell Line Gene Expression Profiles Dataset

From Genomics of Drug Sensitivity in Cancer

mRNA microarray expression profiles for cancer cell lines

KEGG Pathways Dataset (Archived)

From Kyoto Encyclopedia of Genes and Genomes

Sets of proteins participating in pathways from KEGG

KEGG Pathways 2026 Dataset

From Kyoto Encyclopedia of Genes and Genomes

Sets of proteins participating in pathways from KEGG