Name

EZH2 Gene

enhancer of zeste 2 polycomb repressive complex 2 subunit

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

HEIH Gene

hepatocellular carcinoma up-regulated EZH2-associated long non-coding RNA

Biomarker of esophagus squamous cell carcinoma. [provided by Alliance of Genome Resources, Mar 2025]

EZH2-18974828-CHIP-SEQ-MESC Gene Set

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the EZH2-18974828-CHIP-SEQ-MESC transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

EZH2-22144423-EOC-HUMAN Gene Set

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the EZH2-22144423-EOC-HUMAN transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

EZH2-23942234-MYOBLASTS AND MYOTUBES-MOUSE Gene Set

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the EZH2-23942234-MYOBLASTS AND MYOTUBES-MOUSE transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

EZH2 Gene Set

From ChEA Transcription Factor Targets

target genes of the EZH2 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

EED-EZH2 complex Gene Set

From CORUM Protein Complexes

proteins in the EED-EZH2 complex protein complex from the CORUM Protein Complexes dataset.

EZH2 Gene Set

From ENCODE Transcription Factor Targets

target genes of the EZH2 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.

ezh2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ezh2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

WD repeat binding protein EZH2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the WD repeat binding protein EZH2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

EZH2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EZH2 from the Pathway Commons Protein-Protein Interactions dataset.

EZH2-22144423-EOC-HUMAN Gene Set

From ChEA Transcription Factor Targets 2022

target genes of the EZH2-22144423-EOC-HUMAN transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE Gene Set

From ChEA Transcription Factor Targets 2022

target genes of the EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

EZH2 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the EZH2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

EZH2 INHIBITOR Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the EZH2 INHIBITOR drug from theDGIdb Drug Targets 2026 dataset.

EZH2 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the EZH2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.