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LTF Genelactotransferrin This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Activity against both DNA and RNA viruses has been found, including activity against SARS-CoV-2, and HIV. [provided by RefSeq, Jul 2021] |
LTF Gene SetFrom MotifMap Predicted Transcription Factor Targets target genes of the LTF transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. |
LTF Gene SetFrom NURSA Protein-Protein Interactions interacting proteins for LTF from the NURSA Protein-Protein Interactions dataset. |
LTF Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for LTF from the Pathway Commons Protein-Protein Interactions dataset. |
LTF Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the LTF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
LTF Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the LTF gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
LTF granulocyte_Bone marrow_Human Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the LTF granulocyte_Bone marrow_Human cell type from the CellMarker Gene-Cell Type Associations dataset. |
LTF danger signal response pathway Gene SetFrom WikiPathways Pathways 2024 proteins participating in the LTF danger signal response pathway pathway from the WikiPathways Pathways 2024 dataset. |