Name

LTF Gene

lactotransferrin

This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Activity against both DNA and RNA viruses has been found, including activity against SARS-CoV-2, and HIV. [provided by RefSeq, Jul 2021]

LTF Gene Set

From MotifMap Predicted Transcription Factor Targets

target genes of the LTF transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

LTF Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for LTF from the NURSA Protein-Protein Interactions dataset.

LTF Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for LTF from the Pathway Commons Protein-Protein Interactions dataset.

LTF Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the LTF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

LTF Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the LTF gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

LTF granulocyte_Bone marrow_Human Gene Set

From CellMarker Gene-Cell Type Associations

genes associated with the LTF granulocyte_Bone marrow_Human cell type from the CellMarker Gene-Cell Type Associations dataset.

LTF danger signal response pathway Gene Set

From WikiPathways Pathways 2024

proteins participating in the LTF danger signal response pathway pathway from the WikiPathways Pathways 2024 dataset.