Name

MITF Gene

microphthalmia-associated transcription factor

The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]

MITF Gene Set

From ChEA Transcription Factor Targets

target genes of the MITF transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

mitf Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mitf in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MITF Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MITF from the Pathway Commons Protein-Protein Interactions dataset.

MITF Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the MITF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

MITF Gene Set

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the MITF transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

MITF Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the MITF gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

MITF-21258399-MELANOMA-HUMAN Gene Set

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the MITF-21258399-MELANOMA-HUMAN transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

MITF-21258399-MELANOMA-HUMAN Gene Set

From ChEA Transcription Factor Targets 2022

target genes of the MITF-21258399-MELANOMA-HUMAN transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

MITF-M-dependent gene expression Gene Set

From Reactome Pathways 2024

proteins participating in the MITF-M-dependent gene expression pathway from the Reactome Pathways 2024 dataset.

MITF-M-regulated melanocyte development Gene Set

From Reactome Pathways 2024

proteins participating in the MITF-M-regulated melanocyte development pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M dependent genes involved in invasion Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M dependent genes involved in invasion pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M dependent genes involved in metabolism Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M dependent genes involved in metabolism pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M-dependent genes involved in apoptosis Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M-dependent genes involved in apoptosis pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M-dependent genes involved in cell cycle and proliferation Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M-dependent genes involved in cell cycle and proliferation pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M-dependent genes involved in pigmentation Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M-dependent genes involved in pigmentation pathway from the Reactome Pathways 2024 dataset.

Transcriptional and post-translational regulation of MITF-M expression and activity Gene Set

From Reactome Pathways 2024

proteins participating in the Transcriptional and post-translational regulation of MITF-M expression and activity pathway from the Reactome Pathways 2024 dataset.

PMC9159589-pgen.1010207.s019.xlsx-Table_D-MITF-KO_vs_WT_MITF Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC9159589-pgen.1010207.s019.xlsx-Table_D-MITF-KO_vs_WT_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC7857731-elife-63093-supp5.xlsx-ECMdegs-MITF-X6_vs_EVSkMel28-Unnamed_1_MITF Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC7857731-elife-63093-supp5.xlsx-ECMdegs-MITF-X6_vs_EVSkMel28-Unnamed_1_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC7857731-elife-63093-supp5.xlsx-ECMdegs-MITF-X6_vs_EVSkMel28-Unnamed_2_MITF Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC7857731-elife-63093-supp5.xlsx-ECMdegs-MITF-X6_vs_EVSkMel28-Unnamed_2_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC7857731-elife-63093-supp5.xlsx-ECMdegs-MITF-X6_vs_EVSkMel28-Unnamed_36_MITF Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC7857731-elife-63093-supp5.xlsx-ECMdegs-MITF-X6_vs_EVSkMel28-Unnamed_36_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_3_MITF Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_3_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_4_MITF Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_4_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_44_MITF Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_44_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC7902901-Table_12.xlsx-MITF-Unnamed_7_MITF Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC7902901-Table_12.xlsx-MITF-Unnamed_7_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC4989457-13073_2016_339_MOESM9_ESM.xls-MITF-_SURVIVAL-Gene_id_HUGO_ID_MITF Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC4989457-13073_2016_339_MOESM9_ESM.xls-MITF-_SURVIVAL-Gene_id_HUGO_ID_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.