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NEDD8 Geneneural precursor cell expressed, developmentally down-regulated 8 Enables ubiquitin protein ligase binding activity. Acts upstream of or within protein neddylation. Located in cytosol and nucleoplasm. Biomarker of Parkinson's disease and malignant astrocytoma. [provided by Alliance of Genome Resources, Mar 2025] |
NEDD8-MDP1 GeneNEDD8-MDP1 readthrough This locus represents naturally occurring read-through transcription between the neighboring NEDD8 (neural precursor cell expressed, developmentally down-regulated 8) and MDP1 (magnesium-dependent phosphatase 1) genes on chromosome 14. One of the read-through transcripts on this locus encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Jul 2016] |
nedd8 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term nedd8 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
NEDD8 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for NEDD8 from the Pathway Commons Protein-Protein Interactions dataset. |
NEDD8 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the NEDD8 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
NEDD8 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the NEDD8 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
Ubiquitin E3 ligase (CDC34, NEDD8, BTRC, CUL1, SKP1A, RBX1) Gene Setproteins in the Ubiquitin E3 ligase (CDC34, NEDD8, BTRC, CUL1, SKP1A, RBX1) protein complex from the CORUM Protein Complexes dataset. |
nedd8 transferase activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the nedd8 transferase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
nedd8-specific protease activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the nedd8-specific protease activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
nedd8 activating enzyme activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the nedd8 activating enzyme activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
EPI-1571-1 (NEDD8) Gene Setproteins in the EPI-1571-1 (NEDD8) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
NEDD8 transferase activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the NEDD8 transferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
NEDD8 ligase activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the NEDD8 ligase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
NEDD8 conjugating enzyme activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the NEDD8 conjugating enzyme activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
NEDD8 transferase activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the NEDD8 transferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
NEDD8 ligase activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the NEDD8 ligase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
NEDD8 conjugating enzyme activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the NEDD8 conjugating enzyme activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |