NOTCH4

Filters:

Results for "NOTCH4": 1 gene, 8 gene sets

Name
NOTCH4 Gene notch 4 This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
notch4 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term notch4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
NOTCH4 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for NOTCH4 from the Pathway Commons Protein-Protein Interactions dataset.
NOTCH4 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the NOTCH4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
Signaling by NOTCH4 Gene Set From Reactome Pathways 2014 proteins participating in the Signaling by NOTCH4 pathway from the Reactome Pathways dataset.
NOTCH4 Activation and Transmission of Signal to the Nucleus Gene Set From Reactome Pathways 2024 proteins participating in the NOTCH4 Activation and Transmission of Signal to the Nucleus pathway from the Reactome Pathways 2024 dataset.
NOTCH4 Intracellular Domain Regulates Transcription Gene Set From Reactome Pathways 2024 proteins participating in the NOTCH4 Intracellular Domain Regulates Transcription pathway from the Reactome Pathways 2024 dataset.
Negative regulation of NOTCH4 signaling Gene Set From Reactome Pathways 2024 proteins participating in the Negative regulation of NOTCH4 signaling pathway from the Reactome Pathways 2024 dataset.
Signaling by NOTCH4 Gene Set From Reactome Pathways 2024 proteins participating in the Signaling by NOTCH4 pathway from the Reactome Pathways 2024 dataset.