PARP1

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Results for "PARP1": 1 gene, 9 gene sets

Name
PARP1 Gene poly (ADP-ribose) polymerase 1 This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
parp1 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term parp1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
PARP1 Gene Set From Hub Proteins Protein-Protein Interactions interacting proteins for hub protein PARP1 from the curated Hub Proteins Protein-Protein Interactions dataset.
PARP1 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for PARP1 from the Pathway Commons Protein-Protein Interactions dataset.
PARP1 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the PARP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
PARP1 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PARP1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
CDK8-MED6-PARP1 complex Gene Set From CORUM Protein Complexes proteins in the CDK8-MED6-PARP1 complex protein complex from the CORUM Protein Complexes dataset.
WRN-Ku70-Ku80-PARP1 complex Gene Set From CORUM Protein Complexes proteins in the WRN-Ku70-Ku80-PARP1 complex protein complex from the CORUM Protein Complexes dataset.
NCOA6-DNA-PK-Ku-PARP1 complex Gene Set From CORUM Protein Complexes proteins in the NCOA6-DNA-PK-Ku-PARP1 complex protein complex from the CORUM Protein Complexes dataset.
PARP1 INHIBITOR (S)-G9 Gene Set From DGIdb Drug Targets 2026 interacting proteins for the PARP1 INHIBITOR (S)-G9 drug from theDGIdb Drug Targets 2026 dataset.