PNP

Filters:

Results for "PNP": 1 gene, 9 gene sets

Name
PNP Gene purine nucleoside phosphorylase This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008]
pnp Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term pnp in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
PNP Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for PNP from the Pathway Commons Protein-Protein Interactions dataset.
PNP Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the PNP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
PNP Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PNP gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
AMP-PNP Gene Set From Guide to Pharmacology Chemical Ligands of Receptors receptors of the AMP-PNP ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.
PNP/MTAP phosphorylase Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the PNP/MTAP phosphorylase protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine Gene Set From Reactome Pathways 2024 proteins participating in the Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine pathway from the Reactome Pathways 2024 dataset.
PNP POLYMORPH Gene Set From ClinVar Gene-Phenotype Associations 2025 genes associated with the PNP POLYMORPH phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
AMP-PNP Gene Set From DGIdb Drug Targets 2026 interacting proteins for the AMP-PNP drug from theDGIdb Drug Targets 2026 dataset.