Harmonizome 3.0

RAR-related orphan receptor A

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]

RORA antisense RNA 1

RORA antisense RNA 2

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rora in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for RORA from the Pathway Commons Protein-Protein Interactions dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the RORA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the RORA transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the RORA gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From NURSA Protein Complexes

proteins in the SC-6062 (RORA) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From Reactome Pathways 2014

proteins participating in the RORA activates circadian gene expression pathway from the Reactome Pathways dataset.

From Reactome Pathways 2024

proteins participating in the RORA activates gene expression pathway from the Reactome Pathways 2024 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC6488738-mmc6.xlsx-RORA-Target_Gene_RORA transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC11588066-pnas.2410331121.sapp.pdf-140-RORA-AS1_RORA transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.