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SEMA4D Genesema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D Enables identical protein binding activity; semaphorin receptor binding activity; and transmembrane signaling receptor activity. Involved in several processes, including ossification involved in bone maturation; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of neuron projection development. Located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025] |
sema4d Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term sema4d in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
SEMA4D Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for SEMA4D from the Pathway Commons Protein-Protein Interactions dataset. |
SEMA4D Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the SEMA4D gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
SEMA4D Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the SEMA4D gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
Sema4D in semaphorin signaling Gene Setproteins participating in the Sema4D in semaphorin signaling pathway from the Reactome Pathways dataset. |
Sema4D induced cell migration and growth-cone collapse Gene Setproteins participating in the Sema4D induced cell migration and growth-cone collapse pathway from the Reactome Pathways dataset. |
Sema4D mediated inhibition of cell attachment and migration Gene Setproteins participating in the Sema4D mediated inhibition of cell attachment and migration pathway from the Reactome Pathways dataset. |
Sema4D in semaphorin signaling Gene Setproteins participating in the Sema4D in semaphorin signaling pathway from the Reactome Pathways 2024 dataset. |
Sema4D induced cell migration and growth-cone collapse Gene Setproteins participating in the Sema4D induced cell migration and growth-cone collapse pathway from the Reactome Pathways 2024 dataset. |
Sema4D mediated inhibition of cell attachment and migration Gene Setproteins participating in the Sema4D mediated inhibition of cell attachment and migration pathway from the Reactome Pathways 2024 dataset. |
Anti-SEMA4D Monoclonal Antibody VX15/2 Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the Anti-SEMA4D Monoclonal Antibody VX15/2 phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |