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SOS1 Geneson of sevenless homolog 1 (Drosophila) This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008] |
SOS1-IT1 GeneSOS1 intronic transcript 1 |
SOS1 PROTAC 9D Gene Setinteracting proteins for the SOS1 PROTAC 9D drug from theDGIdb Drug Targets 2026 dataset. |
BCL6 PROTAC 15 Gene Setinteracting proteins for the BCL6 PROTAC 15 drug from theDGIdb Drug Targets 2026 dataset. |
BCL6 PROTAC A19 Gene Setinteracting proteins for the BCL6 PROTAC A19 drug from theDGIdb Drug Targets 2026 dataset. |
PROTAC 23 [PMID: 38321747] Gene Setinteracting proteins for the PROTAC 23 [PMID: 38321747] drug from theDGIdb Drug Targets 2026 dataset. |
CDK9 PROTAC C3 Gene Setinteracting proteins for the CDK9 PROTAC C3 drug from theDGIdb Drug Targets 2026 dataset. |
IRAK3 PROTAC 23 Gene Setinteracting proteins for the IRAK3 PROTAC 23 drug from theDGIdb Drug Targets 2026 dataset. |
TBK1 PROTAC 3I Gene Setinteracting proteins for the TBK1 PROTAC 3I drug from theDGIdb Drug Targets 2026 dataset. |
Sos1-Abi1-Eps8 complex Gene Setproteins in the Sos1-Abi1-Eps8 complex protein complex from the CORUM Protein Complexes dataset. |
PLC-gamma-1-SLP-76-SOS1-LAT complex Gene Setproteins in the PLC-gamma-1-SLP-76-SOS1-LAT complex protein complex from the CORUM Protein Complexes dataset. |
CIN85 complex (CIN85, CRK, BCAR1, CBL, PIK3R1, GRB2, SOS1) Gene Setproteins in the CIN85 complex (CIN85, CRK, BCAR1, CBL, PIK3R1, GRB2, SOS1) protein complex from the CORUM Protein Complexes dataset. |
BCR-ABL (p210 fusion protein)-GRB2-SOS1 complex Gene Setproteins in the BCR-ABL (p210 fusion protein)-GRB2-SOS1 complex protein complex from the CORUM Protein Complexes dataset. |
sos1 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term sos1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
BL7507 (SOS1) Gene Setproteins in the BL7507 (SOS1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
SOS1 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for SOS1 from the Pathway Commons Protein-Protein Interactions dataset. |
SOS1 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the SOS1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |