| Name |
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DIABLO Genediablo, IAP-binding mitochondrial protein This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] |
Smac/DIABLO-like Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Smac/DIABLO-like protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Smac/DIABLO protein Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Smac/DIABLO protein protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
SMAC (DIABLO) binds to IAPs Gene Setproteins participating in the SMAC (DIABLO) binds to IAPs pathway from the Reactome Pathways 2024 dataset. |
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes Gene Setproteins participating in the SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes pathway from the Reactome Pathways 2024 dataset. |
diablo Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term diablo in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
DIABLO Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for DIABLO from the Pathway Commons Protein-Protein Interactions dataset. |
DIABLO Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the DIABLO gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
smac Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term smac in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
SMAC-mediated dissociation of IAP:caspase complexes Gene Setproteins participating in the SMAC-mediated dissociation of IAP:caspase complexes pathway from the Reactome Pathways dataset. |
SMAC binds to IAPs Gene Setproteins participating in the SMAC binds to IAPs pathway from the Reactome Pathways dataset. |
SMAC-mediated apoptotic response Gene Setproteins participating in the SMAC-mediated apoptotic response pathway from the Reactome Pathways dataset. |
SMAC, XIAP-regulated apoptotic response Gene Setproteins participating in the SMAC, XIAP-regulated apoptotic response pathway from the Reactome Pathways 2024 dataset. |
SMAC MIMETIC GDC-0917 Gene Setinteracting proteins for the SMAC MIMETIC GDC-0917 drug from theDGIdb Drug Targets 2026 dataset. |