Name

LOC100419644 Gene

sorbitol dehydrogenase pseudogene

SORD Gene

sorbitol dehydrogenase

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]

SORD2P Gene

sorbitol dehydrogenase 2, pseudogene

SORDL Gene

sorbitol dehydrogenase-like

Sorbitol 6-phosphate Gene Set

From DrugBank Drug Targets

interacting proteins for the Sorbitol 6-phosphate drug from the curated DrugBank Drug Targets dataset.

Sorbitol Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Sorbitol from the curated CTD Gene-Chemical Interactions dataset.

2,5-O,O-BIS-{4',4''-AMIDINOPHENYL}-1,4:3,6-DIANHYDRO-D-SORBITOL Gene Set

From DrugBank Drug Targets

interacting proteins for the 2,5-O,O-BIS-{4',4''-AMIDINOPHENYL}-1,4:3,6-DIANHYDRO-D-SORBITOL drug from the curated DrugBank Drug Targets dataset.

2-O-(4'-AMIDINOPHENYL)-5-O-(3''-AMIDINOPHENYL)-1,4:3,6-DIANHYDRO-D-SORBITOL Gene Set

From DrugBank Drug Targets

interacting proteins for the 2-O-(4'-AMIDINOPHENYL)-5-O-(3''-AMIDINOPHENYL)-1,4:3,6-DIANHYDRO-D-SORBITOL drug from the curated DrugBank Drug Targets dataset.

2-O-(3'-AMIDINOPHENYL)-5-O-(4''-AMIDINOPHENYL}-1,4:3,6-DIANHYDRO-D-SORBITOL Gene Set

From DrugBank Drug Targets

interacting proteins for the 2-O-(3'-AMIDINOPHENYL)-5-O-(4''-AMIDINOPHENYL}-1,4:3,6-DIANHYDRO-D-SORBITOL drug from the curated DrugBank Drug Targets dataset.

sorbitol Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sorbitol in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

response to sorbitol Gene Set

From GO Biological Process Annotations 2015

genes participating in the response to sorbitol biological process from the curated GO Biological Process Annotations 2015 dataset.

sorbitol catabolic process Gene Set

From GO Biological Process Annotations 2015

genes participating in the sorbitol catabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.

sorbitol metabolic process Gene Set

From GO Biological Process Annotations 2015

genes participating in the sorbitol metabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.

cellular response to sorbitol Gene Set

From GO Biological Process Annotations 2015

genes participating in the cellular response to sorbitol biological process from the curated GO Biological Process Annotations 2015 dataset.

Sorbitol Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Sorbitol metabolite from the curated HMDB Metabolites of Enzymes dataset.

sorbitol degradation I Gene Set

From HumanCyc Pathways

proteins participating in the sorbitol degradation I pathway from the HumanCyc Pathways dataset.

cellular response to sorbitol Gene Set

From GO Biological Process Annotations 2023

genes participating in the cellular response to sorbitol biological process from the curated GO Biological Process Annotations 2023 dataset.

response to sorbitol Gene Set

From GO Biological Process Annotations 2023

genes participating in the response to sorbitol biological process from the curated GO Biological Process Annotations 2023 dataset.

sorbitol catabolic process Gene Set

From GO Biological Process Annotations 2023

genes participating in the sorbitol catabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

sorbitol metabolic process Gene Set

From GO Biological Process Annotations 2023

genes participating in the sorbitol metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

Sorbitol Gene Set

From MW Enzyme Metabolite Associations

interacting proteins for Sorbitol metabolite from the MW Gene Metabolite Associations dataset.

cellular response to sorbitol Gene Set

From GO Biological Process Annotations 2025

genes participating in the cellular response to sorbitol biological process from the curated GO Biological Process Annotations 2025 dataset.

response to sorbitol Gene Set

From GO Biological Process Annotations 2025

genes participating in the response to sorbitol biological process from the curated GO Biological Process Annotations 2025 dataset.

sorbitol catabolic process Gene Set

From GO Biological Process Annotations 2025

genes participating in the sorbitol catabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

sorbitol metabolic process Gene Set

From GO Biological Process Annotations 2025

genes participating in the sorbitol metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

SORBITOL Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the SORBITOL drug from theDGIdb Drug Targets 2026 dataset.