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GCDH Geneglutaryl-CoA dehydrogenase The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013] |
LOC644203 Geneglutaryl-CoA dehydrogenase, mitochondrial-like |
glutaryl-coenzyme A Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical glutaryl-coenzyme A from the curated CTD Gene-Chemical Interactions dataset. |
Glutaryl-CoA oxidase deficiency Gene SetFrom ClinVar Gene-Phenotype Associations genes associated with the Glutaryl-CoA oxidase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset. |
PARA-NITROBENZYL GLUTARYL GLYCINIC ACID Gene Setinteracting proteins for the PARA-NITROBENZYL GLUTARYL GLYCINIC ACID drug from the curated DrugBank Drug Targets dataset. |
glutaryl-coa dehydrogenase activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the glutaryl-coa dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
Glutaryl-CoA Gene SetFrom HMDB Metabolites of Enzymes interacting proteins for the Glutaryl-CoA metabolite from the curated HMDB Metabolites of Enzymes dataset. |
3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA Gene SetFrom HMDB Metabolites of Enzymes interacting proteins for the 3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA metabolite from the curated HMDB Metabolites of Enzymes dataset. |
glutaryl-CoA degradation Gene SetFrom HumanCyc Pathways proteins participating in the glutaryl-CoA degradation pathway from the HumanCyc Pathways dataset. |
2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA Gene SetFrom HumanCyc Pathways proteins participating in the 2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA pathway from the HumanCyc Pathways dataset. |
glutaryl-CoA dehydrogenase activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the glutaryl-CoA dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
OADH complex synthesizes glutaryl-CoA from 2-OA Gene Setproteins participating in the OADH complex synthesizes glutaryl-CoA from 2-OA pathway from the Reactome Pathways 2024 dataset. |
glutaryl-CoA dehydrogenase activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the glutaryl-CoA dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
Glutaryl-CoA oxidase deficiency Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the Glutaryl-CoA oxidase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |