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LINCS L1000 CMAP Chemical Perturbation Consensus Signatures DatasetFrom LINCS L1000 Connectivity Map Gene association consensus signatures following small molecule perturbation |
RummaGEO Gene Perturbation Signatures DatasetFrom RummaGEO Single gene perturbation signatures produced by querying RummaGEO metadata for knockouts, knockdowns, and over-expression conditions |
RummaGEO Drug Perturbation Signatures DatasetFrom RummaGEO Drug perturbation signatures produced from automatically mined RNA-seq samples from GEO. |
Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures DatasetFrom Replogle et al., Cell, 2022 Gene expression profiles in the K562 cell line following CRISPRi genetic perturbation |
Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures DatasetFrom Replogle et al., Cell, 2022 Gene expression profiles in the K562 cell line following CRISPRi genetic perturbation of essential genes |
Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures DatasetFrom Replogle et al., Cell, 2022 Gene expression profiles in the RPE1 cell line following CRISPRi genetic perturbation of essential genes |
Tahoe Therapeutics Tahoe 100M Perturbation Atlas DatasetFrom Tahoe Therapeutics Single-cell expression data from drug perturbation across cell lines in over 95 million cells |
Sci-Plex Drug Perturbation Signatures DatasetFrom Sci-Plex sciRNA-seq expression profiles for A549, K562, and MCF7 cells treated with 188 compounds at 4 doses |
Carcinogenome Chemical Perturbation Carcinogenicity Signatures DatasetFrom Carcinogenome Chemical carcinogenicity screening using high-throughput transcriptomics assays |
CM4AI KOLF21J CRISPRi Gene Perturbation Atlas DatasetFrom Cell Maps for AI Gene expression profiles in the KOLF2.1J cell line following CRISPRi genetic perturbation |
