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SOX10 GeneSRY (sex determining region Y)-box 10 This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008] |
sox10 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term sox10 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
SOX10 Gene SetFrom JASPAR Predicted Transcription Factor Targets target genes of the SOX10 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. |
SOX10 Gene SetFrom MotifMap Predicted Transcription Factor Targets target genes of the SOX10 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. |
SOX10 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for SOX10 from the Pathway Commons Protein-Protein Interactions dataset. |
SOX10 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the SOX10 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
SOX10 Gene SetFrom JASPAR Predicted Human Transcription Factor Targets 2025 target genes of the SOX10 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. |
SOX10 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the SOX10 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
EGR2 and SOX10-mediated initiation of Schwann cell myelination Gene Setproteins participating in the EGR2 and SOX10-mediated initiation of Schwann cell myelination pathway from the Reactome Pathways 2024 dataset. |