Harmonizome 3.0

ubiquitin specific peptidase 1

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

From NURSA Protein Complexes

proteins in the BL6185 (USP1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the USP1-UAF1 complex protein complex from the CORUM Protein Complexes dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term usp1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for USP1 from the Pathway Commons Protein-Protein Interactions dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the USP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From WikiPathways Pathways 2024

proteins participating in the miR 517 relationship with ARCN1 and USP1 pathway from the WikiPathways Pathways 2024 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the USP1 INHIBITOR 38-P2 drug from theDGIdb Drug Targets 2026 dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the USP1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.