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CD28 GeneCD28 molecule The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] |
CD28 co-stimulation Gene Setproteins participating in the CD28 co-stimulation pathway from the Reactome Pathways dataset. |
CD28 co-stimulation Gene Setproteins participating in the CD28 co-stimulation pathway from the Reactome Pathways 2024 dataset. |
CD28-transactivation complex Gene Setproteins in the CD28-transactivation complex protein complex from the CORUM Protein Complexes dataset. |
ctla4 cd28 haplotypes Gene SetFrom GAD Gene-Disease Associations genes associated with the disease ctla4 cd28 haplotypes in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
cd28 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term cd28 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
T cell antigen CD28 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the T cell antigen CD28 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
CD28 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for CD28 from the Pathway Commons Protein-Protein Interactions dataset. |
Costimulation by the CD28 family Gene Setproteins participating in the Costimulation by the CD28 family pathway from the Reactome Pathways dataset. |
Nef mediated downregulation of CD28 cell surface expression Gene Setproteins participating in the Nef mediated downregulation of CD28 cell surface expression pathway from the Reactome Pathways dataset. |
CD28 dependent PI3K/Akt signaling Gene Setproteins participating in the CD28 dependent PI3K/Akt signaling pathway from the Reactome Pathways dataset. |
CD28 dependent Vav1 pathway Gene Setproteins participating in the CD28 dependent Vav1 pathway pathway from the Reactome Pathways dataset. |
CD28 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the CD28 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
CD4-CD28- T cell_Peripheral blood_Human Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the CD4-CD28- T cell_Peripheral blood_Human cell type from the CellMarker Gene-Cell Type Associations dataset. |
CD4-CD28+ T cell_Peripheral blood_Human Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the CD4-CD28+ T cell_Peripheral blood_Human cell type from the CellMarker Gene-Cell Type Associations dataset. |
CD3/CD28-stimulated T cell_Blood_Human Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the CD3/CD28-stimulated T cell_Blood_Human cell type from the CellMarker Gene-Cell Type Associations dataset. |
CD3/CD28-stimulated NK cell_Blood_Human Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the CD3/CD28-stimulated NK cell_Blood_Human cell type from the CellMarker Gene-Cell Type Associations dataset. |
CD28 dependent PI3K/Akt signaling Gene Setproteins participating in the CD28 dependent PI3K/Akt signaling pathway from the Reactome Pathways 2024 dataset. |
CD28 dependent Vav1 pathway Gene Setproteins participating in the CD28 dependent Vav1 pathway pathway from the Reactome Pathways 2024 dataset. |
Costimulation by the CD28 family Gene Setproteins participating in the Costimulation by the CD28 family pathway from the Reactome Pathways 2024 dataset. |
Nef mediated downregulation of CD28 cell surface expression Gene Setproteins participating in the Nef mediated downregulation of CD28 cell surface expression pathway from the Reactome Pathways 2024 dataset. |
AUTOLOGOUS CCR4-CD30CAR-CD28-CD3ZETA-EXPRESSING T-LYMPHOCYTES Gene Setinteracting proteins for the AUTOLOGOUS CCR4-CD30CAR-CD28-CD3ZETA-EXPRESSING T-LYMPHOCYTES drug from theDGIdb Drug Targets 2026 dataset. |
ALLOGENEIC ANTI-CD19-CAR-CD28-IL-15-EXPRESSING NATURAL KILLER T-CELLS Gene Setinteracting proteins for the ALLOGENEIC ANTI-CD19-CAR-CD28-IL-15-EXPRESSING NATURAL KILLER T-CELLS drug from theDGIdb Drug Targets 2026 dataset. |
AUTOLOGOUS CD19CAR-CD28-CD137/CD27/CD3ZETA-ICASP9-EXPRESSING T-LYMPHOCYTES Gene Setinteracting proteins for the AUTOLOGOUS CD19CAR-CD28-CD137/CD27/CD3ZETA-ICASP9-EXPRESSING T-LYMPHOCYTES drug from theDGIdb Drug Targets 2026 dataset. |
AUTOLOGOUS CD123CAR-CD28-CD3ZETA-EGFRT-EXPRESSING T LYMPHOCYTES MB-102 Gene Setinteracting proteins for the AUTOLOGOUS CD123CAR-CD28-CD3ZETA-EGFRT-EXPRESSING T LYMPHOCYTES MB-102 drug from theDGIdb Drug Targets 2026 dataset. |
AUTOLOGOUS CD30CAR-CD28-CD3ZETA-EXPRESSING T-LYMPHOCYTES Gene Setinteracting proteins for the AUTOLOGOUS CD30CAR-CD28-CD3ZETA-EXPRESSING T-LYMPHOCYTES drug from theDGIdb Drug Targets 2026 dataset. |