Name

FTCDNL1 Gene

formiminotransferase cyclodeaminase N-terminal like

Predicted to enable folic acid binding activity and transferase activity. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Mar 2025]

FTCD Gene

formimidoyltransferase cyclodeaminase

The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Dec 2009]

Cyclodeaminase/cyclohydrolase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cyclodeaminase/cyclohydrolase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

cyclodeaminase Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cyclodeaminase in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

formimidoyltetrahydrofolate cyclodeaminase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the formimidoyltetrahydrofolate cyclodeaminase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

Ornithine cyclodeaminase, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ornithine cyclodeaminase, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ornithine cyclodeaminase/mu-crystallin Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ornithine cyclodeaminase/mu-crystallin protein domain from the InterPro Predicted Protein Domain Annotations dataset.

formimidoyltetrahydrofolate cyclodeaminase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the formimidoyltetrahydrofolate cyclodeaminase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

formimidoyltetrahydrofolate cyclodeaminase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the formimidoyltetrahydrofolate cyclodeaminase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

GTP cyclohydrolase I deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the GTP cyclohydrolase I deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

AICAR TRANSFORMYLASE/IMP CYCLOHYDROLASE DEFICIENCY Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease AICAR TRANSFORMYLASE/IMP CYCLOHYDROLASE DEFICIENCY from the curated CTD Gene-Disease Associations dataset.

cyclohydrolase Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cyclohydrolase in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

regulation of gtp cyclohydrolase i activity Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of gtp cyclohydrolase i activity biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of gtp cyclohydrolase i activity Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of gtp cyclohydrolase i activity biological process from the curated GO Biological Process Annotations 2015 dataset.

cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

gtp cyclohydrolase i activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the gtp cyclohydrolase i activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

imp cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the imp cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

methenyltetrahydrofolate cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the methenyltetrahydrofolate cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

gtp cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the gtp cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

gtp cyclohydrolase binding Gene Set

From GO Molecular Function Annotations 2015

genes performing the gtp cyclohydrolase binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

GTP cyclohydrolase I, feedback regulatory protein Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GTP cyclohydrolase I, feedback regulatory protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GTP cyclohydrolase I domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GTP cyclohydrolase I domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GTP cyclohydrolase I Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GTP cyclohydrolase I protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GTP cyclohydrolase I, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GTP cyclohydrolase I, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GTP cyclohydrolase 1 type 2/Nif3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GTP cyclohydrolase 1 type 2/Nif3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tetrahydrofolate dehydrogenase/cyclohydrolase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tetrahydrofolate dehydrogenase/cyclohydrolase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GTP cyclohydrolase 1 type 2/Nif3, eukaryotic Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GTP cyclohydrolase 1 type 2/Nif3, eukaryotic protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aicar Transformylase Inosine Monophosphate Cyclohydrolase Deficiency Gene Set

From DisGeNET Gene-Disease Associations

genes associated with the disease Aicar Transformylase Inosine Monophosphate Cyclohydrolase Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

negative regulation of GTP cyclohydrolase I activity Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of GTP cyclohydrolase I activity biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of GTP cyclohydrolase I activity Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of GTP cyclohydrolase I activity biological process from the curated GO Biological Process Annotations 2023 dataset.

methenyltetrahydrofolate cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the methenyltetrahydrofolate cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

GTP cyclohydrolase I activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the GTP cyclohydrolase I activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

IMP cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the IMP cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

GTP cyclohydrolase binding Gene Set

From GO Molecular Function Annotations 2023

genes performing the GTP cyclohydrolase binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

GTP cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the GTP cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

methenyltetrahydrofolate cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the methenyltetrahydrofolate cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

GTP cyclohydrolase I activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the GTP cyclohydrolase I activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

IMP cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the IMP cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

GTP cyclohydrolase binding Gene Set

From GO Molecular Function Annotations 2025

genes performing the GTP cyclohydrolase binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

GTP cyclohydrolase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the GTP cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

GTP cyclohydrolase I deficiency Gene Set

From ClinVar Gene-Phenotype Associations 2025

genes associated with the GTP cyclohydrolase I deficiency phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.