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IRF7 Geneinterferon regulatory factor 7 This gene encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. It has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. The encoded protein plays an important role in the innate immune response against DNA and RNA viruses. [provided by RefSeq, Jul 2021] |
irf7 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term irf7 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
IRF7 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for IRF7 from the Pathway Commons Protein-Protein Interactions dataset. |
IRF7 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the IRF7 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
IRF7 Gene SetFrom JASPAR Predicted Human Transcription Factor Targets 2025 target genes of the IRF7 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. |
IRF7 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the IRF7 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon Gene Setproteins participating in the Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon pathway from the Reactome Pathways dataset. |
TRAF6 mediated IRF7 activation Gene Setproteins participating in the TRAF6 mediated IRF7 activation pathway from the Reactome Pathways dataset. |
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling Gene Setproteins participating in the TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling pathway from the Reactome Pathways dataset. |
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) Gene Setproteins participating in the Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) pathway from the Reactome Pathways 2024 dataset. |
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 Gene Setproteins participating in the Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 pathway from the Reactome Pathways 2024 dataset. |
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation Gene Setproteins participating in the Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation pathway from the Reactome Pathways 2024 dataset. |
TICAM1-dependent activation of IRF3/IRF7 Gene Setproteins participating in the TICAM1-dependent activation of IRF3/IRF7 pathway from the Reactome Pathways 2024 dataset. |
TRAF6 mediated IRF7 activation Gene Setproteins participating in the TRAF6 mediated IRF7 activation pathway from the Reactome Pathways 2024 dataset. |
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling Gene Setproteins participating in the TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling pathway from the Reactome Pathways 2024 dataset. |
PMC8755441-mmc3.xlsx-IRF7-down-Symbol_IRF7 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC8755441-mmc3.xlsx-IRF7-down-Symbol_IRF7 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_IRF7 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_IRF7 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_1_IRF7 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_1_IRF7 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC8755441-mmc3.xlsx-IRF7-Up-stat1-k562_IRF7 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC8755441-mmc3.xlsx-IRF7-Up-stat1-k562_IRF7 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC8755441-mmc3.xlsx-IRF7-Up-stat1-hela_IRF7 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC8755441-mmc3.xlsx-IRF7-Up-stat1-hela_IRF7 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC8755441-mmc3.xlsx-IRF7-Up-IRF7Del246-647_IRF7 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC8755441-mmc3.xlsx-IRF7-Up-IRF7Del246-647_IRF7 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |