Name

MPI Gene

mannose phosphate isomerase

Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

MPI-0485520 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the MPI-0485520 drug from theDGIdb Drug Targets 2026 dataset.

Defective MPI causes MPI-CDG Gene Set

From Reactome Pathways 2024

proteins participating in the Defective MPI causes MPI-CDG pathway from the Reactome Pathways 2024 dataset.

MPI-674 Gene Set

From DrugBank Drug Targets

interacting proteins for the MPI-674 drug from the curated DrugBank Drug Targets dataset.

MPI Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MPI from the Pathway Commons Protein-Protein Interactions dataset.

MPI-0479605-HCL Gene Set

From DeepCoverMOA Drug Mechanisms of Action

proteins with high or low expression in MPI-0479605-HCL relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.

MPI-congenital disorder of glycosylation Gene Set

From ClinVar Gene-Phenotype Associations 2025

genes associated with the MPI-congenital disorder of glycosylation phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

MPI-0479605 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the MPI-0479605 drug from theDGIdb Drug Targets 2026 dataset.

MPI-674 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the MPI-674 drug from theDGIdb Drug Targets 2026 dataset.

MPI Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the MPI gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.