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NFE2L2 Genenuclear factor, erythroid 2-like 2 This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015] |
NFE2L2 Gene SetFrom ChEA Transcription Factor Targets target genes of the NFE2L2 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. |
nfe2l2 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term nfe2l2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
NFE2L2 Gene SetFrom MotifMap Predicted Transcription Factor Targets target genes of the NFE2L2 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. |
NFE2L2 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for NFE2L2 from the Pathway Commons Protein-Protein Interactions dataset. |
NFE2L2 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the NFE2L2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
Nfe2l2 Gene SetFrom JASPAR Predicted Mouse Transcription Factor Targets 2025 target genes of the Nfe2l2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2925 dataset. |
NFE2L2 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the NFE2L2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
NFE2L2-22581777-LYMPHOBLASTOID-HUMAN Gene SetFrom ChEA Transcription Factor Binding Site Profiles genes with transcription factor binding evidence in the NFE2L2-22581777-LYMPHOBLASTOID-HUMAN transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset. |
NFE2L2-20460467-MEF-MOUSE Gene SetFrom ChEA Transcription Factor Binding Site Profiles genes with transcription factor binding evidence in the NFE2L2-20460467-MEF-MOUSE transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset. |
NFE2L2-22581777-LYMPHOBLASTOID-HUMAN Gene SetFrom ChEA Transcription Factor Targets 2022 target genes of the NFE2L2-22581777-LYMPHOBLASTOID-HUMAN transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. |
NFE2L2-20460467-MEFS-MOUSE Gene SetFrom ChEA Transcription Factor Targets 2022 target genes of the NFE2L2-20460467-MEFS-MOUSE transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. |
Photodynamic therapy induced NFE2L2 NRF2 survival signaling Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Photodynamic therapy induced NFE2L2 NRF2 survival signaling pathway from the WikiPathways Pathways 2024 dataset. |
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 Gene Setproteins participating in the GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 pathway from the Reactome Pathways 2024 dataset. |
KEAP1-NFE2L2 pathway Gene Setproteins participating in the KEAP1-NFE2L2 pathway pathway from the Reactome Pathways 2024 dataset. |
NFE2L2 regulates pentose phosphate pathway genes Gene Setproteins participating in the NFE2L2 regulates pentose phosphate pathway genes pathway from the Reactome Pathways 2024 dataset. |
NFE2L2 regulating ER-stress associated genes Gene Setproteins participating in the NFE2L2 regulating ER-stress associated genes pathway from the Reactome Pathways 2024 dataset. |
NFE2L2 regulating MDR associated enzymes Gene Setproteins participating in the NFE2L2 regulating MDR associated enzymes pathway from the Reactome Pathways 2024 dataset. |
NFE2L2 regulating TCA cycle genes Gene Setproteins participating in the NFE2L2 regulating TCA cycle genes pathway from the Reactome Pathways 2024 dataset. |
NFE2L2 regulating anti-oxidant/detoxification enzymes Gene Setproteins participating in the NFE2L2 regulating anti-oxidant/detoxification enzymes pathway from the Reactome Pathways 2024 dataset. |
NFE2L2 regulating inflammation associated genes Gene Setproteins participating in the NFE2L2 regulating inflammation associated genes pathway from the Reactome Pathways 2024 dataset. |
NFE2L2 regulating tumorigenic genes Gene Setproteins participating in the NFE2L2 regulating tumorigenic genes pathway from the Reactome Pathways 2024 dataset. |
Nuclear events mediated by NFE2L2 Gene Setproteins participating in the Nuclear events mediated by NFE2L2 pathway from the Reactome Pathways 2024 dataset. |
Regulation of NFE2L2 gene expression Gene Setproteins participating in the Regulation of NFE2L2 gene expression pathway from the Reactome Pathways 2024 dataset. |
PMC6772115-JCB-120-18332-s003.xlsx-NFE2L2-Dataset_Gene_ID_NFE2L2 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC6772115-JCB-120-18332-s003.xlsx-NFE2L2-Dataset_Gene_ID_NFE2L2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC5309296-18_2016_2401_MOESM3_ESM.xlsx-NFE2L2-Unnamed_0_NFE2L2 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC5309296-18_2016_2401_MOESM3_ESM.xlsx-NFE2L2-Unnamed_0_NFE2L2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
