PDGFRB

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Results for "PDGFRB": 1 gene, 13 gene sets

Name
PDGFRB Gene platelet-derived growth factor receptor, beta polypeptide The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
pdgfrb Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term pdgfrb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
PDGFRB Gene Set From Hub Proteins Protein-Protein Interactions interacting proteins for hub protein PDGFRB from the curated Hub Proteins Protein-Protein Interactions dataset.
PDGFRB Gene Set From KEA Substrates of Kinases substrates of the kinase PDGFRB from the curated KEA Substrates of Kinases dataset.
PDGFRB Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for PDGFRB from the Pathway Commons Protein-Protein Interactions dataset.
PDGFRB Gene Set From PhosphoSitePlus Substrates of Kinases substrates of the kinase PDGFRB from the curated PhosphoSitePlus Substrates of Kinases dataset.
PDGFRB Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the PDGFRB gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
PDGFRB Gene Set From Kinase Library Tyrosine Kinome Atlas substrates of the kinase PDGFRB from the Kinase Library Tyrosine Kinome Atlas dataset.
PDGFRB Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PDGFRB gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
Sh3kbp1-Cblb-Pdgfrb complex Gene Set From CORUM Protein Complexes proteins in the Sh3kbp1-Cblb-Pdgfrb complex protein complex from the CORUM Protein Complexes dataset.
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins Gene Set From Reactome Pathways 2024 proteins participating in the Signaling by cytosolic PDGFRA and PDGFRB fusion proteins pathway from the Reactome Pathways 2024 dataset.
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB Gene Set From Reactome Pathways 2024 proteins participating in the Signaling by membrane-tethered fusions of PDGFRA or PDGFRB pathway from the Reactome Pathways 2024 dataset.
Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 Gene Set From DISEASES Curated Gene-Disease Association Evidence Scores 2025 genes involed in the disease Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 Gene Set From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 genes co-occuring with the disease Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.