Name

PPOX Gene

protoporphyrinogen oxidase

This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Protoporphyrinogen IX Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Protoporphyrinogen IX metabolite from the curated HMDB Metabolites of Enzymes dataset.

Protoporphyrinogen IX Gene Set

From MW Enzyme Metabolite Associations

interacting proteins for Protoporphyrinogen IX metabolite from the MW Gene Metabolite Associations dataset.

protoporphyrinogen Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical protoporphyrinogen from the curated CTD Gene-Chemical Interactions dataset.

protoporphyrinogen ix biosynthetic process Gene Set

From GO Biological Process Annotations 2015

genes participating in the protoporphyrinogen ix biosynthetic process biological process from the curated GO Biological Process Annotations 2015 dataset.

protoporphyrinogen ix metabolic process Gene Set

From GO Biological Process Annotations 2015

genes participating in the protoporphyrinogen ix metabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.

oxygen-dependent protoporphyrinogen oxidase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the oxygen-dependent protoporphyrinogen oxidase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

protoporphyrinogen oxidase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the protoporphyrinogen oxidase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

Protoporphyrinogen oxidase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Protoporphyrinogen oxidase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Protoporphyrinogen oxidase, C-terminal domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Protoporphyrinogen oxidase, C-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

protoporphyrinogen IX metabolic process Gene Set

From GO Biological Process Annotations 2023

genes participating in the protoporphyrinogen IX metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

protoporphyrinogen IX biosynthetic process Gene Set

From GO Biological Process Annotations 2023

genes participating in the protoporphyrinogen IX biosynthetic process biological process from the curated GO Biological Process Annotations 2023 dataset.

oxygen-dependent protoporphyrinogen oxidase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the oxygen-dependent protoporphyrinogen oxidase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

protoporphyrinogen oxidase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the protoporphyrinogen oxidase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

protoporphyrinogen IX metabolic process Gene Set

From GO Biological Process Annotations 2025

genes participating in the protoporphyrinogen IX metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

protoporphyrinogen IX biosynthetic process Gene Set

From GO Biological Process Annotations 2025

genes participating in the protoporphyrinogen IX biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.

oxygen-dependent protoporphyrinogen oxidase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the oxygen-dependent protoporphyrinogen oxidase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

protoporphyrinogen oxidase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the protoporphyrinogen oxidase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.