Harmonizome 3.0

proliferating cell nuclear antigen

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

PCNA antisense RNA 1

PCNA clamp associated factor

Enables chromatin binding activity and molecular adaptor activity. Involved in several processes, including DNA metabolic process; centrosome cycle; and response to UV. Located in centrosome; nucleus; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

From NURSA Protein Complexes

proteins in the SC-56 (PCNA) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the pcna-p21 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the pcna complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the pcna-p21 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the pcna complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From CORUM Protein Complexes

proteins in the PCNA-DNA polymerase delta complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PCNA-MutS-alpha-DNA initial complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the ING1-p300-PCNA complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PCNA-KU antigen complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the DNMT1-G9a-PCNA complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PCNA-MSH2-MSH6 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the CDC2-PCNA-CCNB1-GADD45A complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PCNA-p21 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PCNA-PAF complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the p33ING1b-PCNA complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the CDC2-PCNA-CCNB1-GADD45B complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the ING1-PCNA complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PCNA-MLH1-PMS1 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PCNA-MutS-alpha-MutL-alpha-DNA complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the CDC2-PCNA-CCNB1-GADD45G complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PCNA-CHL12-RFC2-5 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PCNA-DNA ligase complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the EXO1-MLH1-PCNA complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PCNA-RFC2-5 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PCNA homotrimer complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the MSH2-MLH1-PMS2-PCNA DNA-repair initiation complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the KIN17-PCNA-RPA70 complex protein complex from the CORUM Protein Complexes dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pcna in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Cellular Component Annotations 2015

proteins localized to the pcna-p21 complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the pcna complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein PCNA from the curated Hub Proteins Protein-Protein Interactions dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Proliferating cell nuclear antigen, PCNA protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Proliferating cell nuclear antigen, PCNA, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Proliferating cell nuclear antigen, PCNA, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Proliferating cell nuclear antigen, PCNA, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for PCNA from the MSigDB Cancer Gene Co-expression Modules dataset.

From NURSA Protein-Protein Interactions

interacting proteins for PCNA from the NURSA Protein-Protein Interactions dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for PCNA from the Pathway Commons Protein-Protein Interactions dataset.

From Reactome Pathways 2024

proteins participating in the PCNA-Dependent Long Patch Base Excision Repair pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Recognition of DNA damage by PCNA-containing replication complex pathway from the Reactome Pathways 2024 dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the PCNA complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the PCNA-p21 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the PCNA complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the PCNA-p21 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the PCNA gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.