Name

TGFBR1 Gene

transforming growth factor, beta receptor 1

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

tgfbr1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tgfbr1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TGFBR1 Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein TGFBR1 from the curated Hub Proteins Protein-Protein Interactions dataset.

TGFBR1 Gene Set

From KEA Substrates of Kinases

substrates of the kinase TGFBR1 from the curated KEA Substrates of Kinases dataset.

TGFBR1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TGFBR1 from the Pathway Commons Protein-Protein Interactions dataset.

TGFBR1 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase TGFBR1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

TGFBR1 Gene Set

From Kinase Library Serine Threonine Kinome Atlas

substrates of the kinase TGFBR1 from the Kinase Library Serine Threonine Kinome Atlas dataset.

TGFBR1 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the TGFBR1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

TGFBR1 KD Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways dataset.

Loss of Function of TGFBR1 in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the Loss of Function of TGFBR1 in Cancer pathway from the Reactome Pathways dataset.

TGFBR1 LBD Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways dataset.

Loss of Function of TGFBR1 in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the Loss of Function of TGFBR1 in Cancer pathway from the Reactome Pathways 2024 dataset.

TGFBR1 KD Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

TGFBR1 LBD Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.