TLR3

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Results for "TLR3": 1 gene, 10 gene sets

Name
TLR3 Gene toll-like receptor 3 The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It thus plays a role in host defense against multiple viruses. [provided by RefSeq, Jul 2021]
tlr3 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term tlr3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
TLR3 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for TLR3 from the Pathway Commons Protein-Protein Interactions dataset.
TLR3 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the TLR3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
TLR3 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the TLR3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
Toll Like Receptor 3 (TLR3) Cascade Gene Set From Reactome Pathways 2014 proteins participating in the Toll Like Receptor 3 (TLR3) Cascade pathway from the Reactome Pathways dataset.
TRIF-mediated TLR3/TLR4 signaling Gene Set From Reactome Pathways 2014 proteins participating in the TRIF-mediated TLR3/TLR4 signaling pathway from the Reactome Pathways dataset.
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation Gene Set From Reactome Pathways 2024 proteins participating in the Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation pathway from the Reactome Pathways 2024 dataset.
TLR3 deficiency - HSE Gene Set From Reactome Pathways 2024 proteins participating in the TLR3 deficiency - HSE pathway from the Reactome Pathways 2024 dataset.
TLR3-mediated TICAM1-dependent programmed cell death Gene Set From Reactome Pathways 2024 proteins participating in the TLR3-mediated TICAM1-dependent programmed cell death pathway from the Reactome Pathways 2024 dataset.
Toll Like Receptor 3 (TLR3) Cascade Gene Set From Reactome Pathways 2024 proteins participating in the Toll Like Receptor 3 (TLR3) Cascade pathway from the Reactome Pathways 2024 dataset.