Harmonizome 3.0

G protein-coupled receptor 142

GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008]

zinc finger protein 142

The protein encoded by this gene belongs to the Kruppel family of C2H2-type zinc finger proteins. It contains 31 C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]

RNA, 5S ribosomal pseudogene 142

chromosome 10 open reading frame 142

coiled-coil domain containing 142

microRNA 142

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

chromosome 14 open reading frame 142

Involved in tRNA threonylcarbamoyladenosine modification. Located in cytosol; nucleolus; and nucleoplasm. Part of EKC/KEOPS complex. Implicated in Galloway-Mowat syndrome. [provided by Alliance of Genome Resources, Mar 2025]

chromosome 9 open reading frame 142

The protein encoded by this gene plays a role in the nonhomologous end joining (NHEJ) pathway of DNA double-strand break repair. The encoded protein may function to stabilize the Ku70/Ku80 heterodimer to facilitate the assembly and maintain the stability of the NHEJ complex. [provided by RefSeq, Jul 2016]

From DeepCoverMOA Drug Mechanisms of Action

proteins with high or low expression in kb NB 142-70 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the tolbutamide-142 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical HS 142-1 from the curated CTD Gene-Chemical Interactions dataset.

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the miR-142-3p_OE_GSE28456_470_human_Raji cells (B lymphocytes) gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the NIP-142 ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Coiled-coil domain-containing protein 142 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From MiRTarBase microRNA Targets

target genes of the hsa-miR-142-5p microRNA in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.

From MiRTarBase microRNA Targets

target genes of the hsa-miR-142-3p microRNA in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.

From TargetScan Predicted Conserved microRNA Targets

target genes of the hsa-miR-142-3p microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

From TargetScan Predicted Conserved microRNA Targets

target genes of the hsa-miR-142-5p microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

From TargetScan Predicted Nonconserved microRNA Targets

target genes of the hsa-miR-142-3p microRNA predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.

From TargetScan Predicted Nonconserved microRNA Targets

target genes of the hsa-miR-142-5p microRNA predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.

From DeepCoverMOA Drug Mechanisms of Action

proteins with high or low expression in HFI-142 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.

From HuBMAP ASCT+B Annotations

biomarker genes for the Brain_CT2_DLIT 142 cell type from the HuBMAP ASCT+B dataset.

From HuBMAP ASCT+B Augmented with RNA-seq Coexpression

biomarker genes for the Brain_CT2_DLIT 142 cell type from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset.

From DGIdb Drug Targets 2026

interacting proteins for the NIP-142 drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the LISTERIA MONOCYTOGENES-LLO-PSA VACCINE ADXS31-142 drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the HS-142-1 drug from theDGIdb Drug Targets 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC4172779-13048_2014_87_MOESM1_ESM.pdf-142-ZNF383_ZNF383 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC5725737-IJC-142-297-s013.xlsx-DTC_mna_vs_TUM_mna-DTC_MYCN-high_vs_TU_MYCN-high_MYCN transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC11620327-aln-142-052-s001.pdf-40-FLI1_FLI1 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC11732233-mmc1.pdf-142-NANOG_NANOG transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.