Name

MZT2A Gene

mitotic spindle organizing protein 2A

Located in centrosome; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

MZT2B Gene

mitotic spindle organizing protein 2B

Located in cytosol; microtubule cytoskeleton; and nucleoplasm. Part of gamma-tubulin ring complex. [provided by Alliance of Genome Resources, Mar 2025]

MINOS1P4 Gene

mitochondrial inner membrane organizing system 1 pseudogene 4

MINOS1P3 Gene

mitochondrial inner membrane organizing system 1 pseudogene 3

MINOS1P2 Gene

mitochondrial inner membrane organizing system 1 pseudogene 2

MINOS1P1 Gene

mitochondrial inner membrane organizing system 1 pseudogene 1

MINOS1 Gene

mitochondrial inner membrane organizing system 1

Involved in cristae formation. Located in mitochondrion. Part of MIB complex; MICOS complex; and SAM complex. [provided by Alliance of Genome Resources, Mar 2025]

MZT1P2 Gene

mitotic spindle organizing protein 1 pseudogene 2

MZT1 Gene

mitotic spindle organizing protein 1

Involved in gamma-tubulin complex localization. Located in centrosome and spindle. Part of gamma-tubulin ring complex. [provided by Alliance of Genome Resources, Mar 2025]

MICOS10 Gene

mitochondrial contact site and cristae organizing system subunit 10

Involved in cristae formation. Located in mitochondrion. Part of MIB complex; MICOS complex; and SAM complex. [provided by Alliance of Genome Resources, Mar 2025]

MICOS13 Gene

mitochondrial contact site and cristae organizing system subunit 13

Involved in cristae formation. Located in mitochondrial crista junction and nucleoplasm. Part of MICOS complex. Implicated in combined oxidative phosphorylation deficiency 37. [provided by Alliance of Genome Resources, Mar 2025]

MAP10 Gene

microtubule-associated protein 10

Enables microtubule binding activity. Involved in microtubule cytoskeleton organization; positive regulation of cytokinesis; and regulation of microtubule-based process. Located in microtubule cytoskeleton and midbody. [provided by Alliance of Genome Resources, Mar 2025]

MAP1A Gene

microtubule-associated protein 1A

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development. [provided by RefSeq, Jul 2008]

MAP1B Gene

microtubule-associated protein 1B

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008]

MAP1S Gene

microtubule-associated protein 1S

Enables DNA binding activity and cytoskeletal protein binding activity. Involved in metaphase chromosome alignment; microtubule cytoskeleton organization; and neuron projection morphogenesis. Located in several cellular components, including microtubule cytoskeleton; nuclear lumen; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

MAP1LC3B2 Gene

microtubule-associated protein 1 light chain 3 beta 2

Predicted to enable microtubule binding activity; phosphatidylethanolamine binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in cellular response to nitrogen starvation and macroautophagy. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Mar 2025]

MARK4 Gene

MAP/microtubule affinity-regulating kinase 4

This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

MARK1 Gene

MAP/microtubule affinity-regulating kinase 1

Enables several functions, including ATP binding activity; magnesium ion binding activity; and phospholipid binding activity. Involved in intracellular signal transduction; negative regulation of epithelial to mesenchymal transition; and protein phosphorylation. Located in cytoplasm; dendrite; and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

MARK2 Gene

MAP/microtubule affinity-regulating kinase 2

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]

MARK3 Gene

MAP/microtubule affinity-regulating kinase 3

The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

MAP2 Gene

microtubule-associated protein 2

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]

MAP6 Gene

microtubule-associated protein 6

This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

MAP7 Gene

microtubule-associated protein 7

The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

MAP4 Gene

microtubule-associated protein 4

The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

MAPT Gene

microtubule-associated protein tau

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

LOC105376502 Gene

microtubule cross-linking factor 1-like

RMDN2 Gene

regulator of microtubule dynamics 2

Enables microtubule binding activity. Located in Golgi apparatus; cytosol; and spindle. [provided by Alliance of Genome Resources, Mar 2025]

RMDN3 Gene

regulator of microtubule dynamics 3

Enables microtubule binding activity. Involved in intracellular calcium ion homeostasis. Located in several cellular components, including intercellular bridge; mitochondrial outer membrane; and spindle. [provided by Alliance of Genome Resources, Mar 2025]

RMDN1 Gene

regulator of microtubule dynamics 1

Enables microtubule binding activity. Predicted to be involved in attachment of mitotic spindle microtubules to kinetochore and mitotic spindle organization. Located in mitotic spindle pole and spindle microtubule. [provided by Alliance of Genome Resources, Mar 2025]

MTUS1 Gene

microtubule associated tumor suppressor 1

This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]

MTUS2 Gene

microtubule associated tumor suppressor candidate 2

Enables microtubule binding activity and protein homodimerization activity. Located in centrosome; cytoplasmic microtubule; and intercellular bridge. Part of nucleus. [provided by Alliance of Genome Resources, Mar 2025]

HOOK2 Gene

hook microtubule-tethering protein 2

Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]

HOOK3 Gene

hook microtubule-tethering protein 3

Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]

HOOK1 Gene

hook microtubule-tethering protein 1

This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

JAKMIP3 Gene

Janus kinase and microtubule interacting protein 3

Predicted to enable kinase binding activity and microtubule binding activity. Predicted to be located in Golgi apparatus and membrane. [provided by Alliance of Genome Resources, Mar 2025]

JAKMIP2 Gene

janus kinase and microtubule interacting protein 2

The protein encoded by this gene is reported to be a component of the Golgi matrix. It may act as a golgin protein by negatively regulating transit of secretory cargo and by acting as a structural scaffold of the Golgi. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

JAKMIP1 Gene

janus kinase and microtubule interacting protein 1

Enables GABA receptor binding activity and RNA binding activity. Involved in cognition. Located in membrane. Part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Mar 2025]

LOC100421494 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene

FLJ25758 Gene

MAP/microtubule affinity-regulating kinase 1 pseudogene

MASTL Gene

microtubule associated serine/threonine kinase-like

This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Feb 2010]

MAST1 Gene

microtubule associated serine/threonine kinase 1

This gene is a member of the microtubule-associated serine/threonine kinase (MAST) family. The protein encoded by this gene has an N-terminal serine/threonine kinase domain followed by a postsynaptic density protein-95/discs large/zona occludens-1 (PDZ) domain. In mouse and rat, the orthologous protein associates with the cytoskeleton and can bind both beta-2-syntrophin and neuronal nitric oxide synthase (nNOS) through its PDZ domain. In mouse and rat, this protein also co-localizes with dystrophin- and utrophin-associated protein complexes (DAPC/UAPC) in the vascular endothelium of the central nervous system. [provided by RefSeq, May 2017]

MAST2 Gene

microtubule associated serine/threonine kinase 2

Enables phosphatase binding activity. Predicted to be involved in several processes, including protein phosphorylation; regulation of interleukin-12 production; and spermatid differentiation. Predicted to be located in cytoplasm; cytoskeleton; and plasma membrane. Predicted to be active in microtubule cytoskeleton. [provided by Alliance of Genome Resources, Mar 2025]

MAST3 Gene

microtubule associated serine/threonine kinase 3

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cytoskeleton organization and intracellular signal transduction. Predicted to be located in cytoplasm. Implicated in developmental and epileptic encephalopathy 108. [provided by Alliance of Genome Resources, Mar 2025]

MAST4 Gene

microtubule associated serine/threonine kinase family member 4

This gene encodes a member of the microtubule-associated serine/threonine protein kinases. The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]

LOC100420584 Gene

microtubule-associated protein 6 pseudogene

MTCL1 Gene

microtubule crosslinking factor 1

Enables microtubule binding activity. Involved in chromosome segregation. Located in kinetochore; midbody; and spindle. [provided by Alliance of Genome Resources, Mar 2025]

TPX2 Gene

TPX2, microtubule-associated

Enables importin-alpha family protein binding activity; molecular adaptor activity; and protein kinase binding activity. Involved in activation of protein kinase activity; microtubule cytoskeleton organization; and negative regulation of microtubule depolymerization. Located in intercellular bridge; nucleoplasm; and spindle. Is active in spindle. [provided by Alliance of Genome Resources, Mar 2025]

MARK2P12 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 12

MITD1 Gene

MIT, microtubule interacting and transport, domain containing 1

Abscission, the separation of daughter cells at the end of cytokinesis, is effected by endosomal sorting complexes required for transport III (ESCRT-III). The protein encoded by this gene functions as a homodimer, with the N-termini binding to a subset of ESCRT-III subunits and the C-termini binding to membranes. The encoded protein regulates ESCRT-III activity and is required for proper cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

MARK2P8 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 8

MARK2P9 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 9

MARK2P4 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 4

MARK2P5 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 5

MARK2P6 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 6

MARK2P7 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 7

MARK2P1 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 1

MARK2P2 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 2

MARK2P3 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 3

LOC100421508 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene

LOC100421505 Gene

MAP/microtubule affinity-regulating kinase 4 pseudogene

EML2 Gene

echinoderm microtubule associated protein like 2

Enables microtubule binding activity. Involved in negative regulation of microtubule polymerization and regulation of microtubule nucleation. Located in mitotic spindle. [provided by Alliance of Genome Resources, Mar 2025]

EML3 Gene

echinoderm microtubule associated protein like 3

Predicted to enable microtubule binding activity. Involved in mitotic metaphase chromosome alignment and regulation of mitotic spindle assembly. Located in several cellular components, including midbody; mitotic spindle microtubule; and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

EML1 Gene

echinoderm microtubule associated protein like 1

Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

EML6 Gene

echinoderm microtubule associated protein like 6

Predicted to enable microtubule binding activity. Predicted to be located in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Mar 2025]

EML4 Gene

echinoderm microtubule associated protein like 4

This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]

EML5 Gene

echinoderm microtubule associated protein like 5

Predicted to enable microtubule binding activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Mar 2025]

MACF1 Gene

microtubule-actin crosslinking factor 1

This gene encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. The encoded protein is a member of a family of proteins that form bridges between different cytoskeletal elements. This protein facilitates actin-microtubule interactions at the cell periphery and couples the microtubule network to cellular junctions. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, May 2013]

MAP1LC3BP1 Gene

microtubule-associated protein 1 light chain 3 beta pseudogene 1

LOC100421558 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene

LOC387869 Gene

microtubule-associated protein 1 light chain 3 beta pseudogene

LOC100421504 Gene

MAP/microtubule affinity-regulating kinase 4 pseudogene

LOC100287355 Gene

microtubule-associated protein 1 light chain 3 beta pseudogene

MAP9 Gene

microtubule-associated protein 9

ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]).[supplied by OMIM, Mar 2008]

MAPRE1 Gene

microtubule-associated protein, RP/EB family, member 1

The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]

MAPRE3 Gene

microtubule-associated protein, RP/EB family, member 3

The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008]

MAPRE2 Gene

microtubule-associated protein, RP/EB family, member 2

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

MARK2P16 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 16

MARK2P17 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 17

MARK2P14 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 14

MARK2P15 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 15

MARK2P13 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 13

MARK2P10 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 10

MARK2P11 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 11

MICAL1 Gene

microtubule associated monooxygenase, calponin and LIM domain containing 1

This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

MICAL2 Gene

microtubule associated monooxygenase, calponin and LIM domain containing 2

The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]

MICAL3 Gene

microtubule associated monooxygenase, calponin and LIM domain containing 3

Enables actin binding activity and molecular adaptor activity. Involved in actin filament depolymerization. Located in several cellular components, including Flemming body; intercellular bridge; and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

MAP1LC3P Gene

microtubule-associated protein 1 light chain 3 pseudogene

MAP1LC3A Gene

microtubule-associated protein 1 light chain 3 alpha

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012]

MAP1LC3C Gene

microtubule-associated protein 1 light chain 3 gamma

Autophagy is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. MAP1LC3C is an ortholog of the yeast autophagosome protein Atg8 (He et al., 2003 [PubMed 12740394]).[supplied by OMIM, Nov 2010]

MAP1LC3B Gene

microtubule-associated protein 1 light chain 3 beta

The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008]

HSA251708 Gene

microtubule-binding protein-like

MARK3P1 Gene

MAP/microtubule affinity-regulating kinase 3 pseudogene 1

MARK3P3 Gene

MAP/microtubule affinity-regulating kinase 3 pseudogene 3

MARK3P2 Gene

MAP/microtubule affinity-regulating kinase 3 pseudogene 2

LOC100533755 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene

LOC100421511 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene

GS1-279B7.1 Gene

microtubule-associated protein 1 light chain 3 beta pseudogene

JPT2 Gene

Jupiter microtubule associated homolog 2

Involved in endocytosis involved in viral entry into host cell and regulation of calcium-mediated signaling. Located in cytosol; nucleus; and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

JPT1 Gene

Jupiter microtubule associated homolog 1

Located in cytosol; intercellular bridge; and microtubule cytoskeleton. [provided by Alliance of Genome Resources, Mar 2025]

MATCAP2 Gene

microtubule associated tyrosine carboxypeptidase 2

Predicted to enable carboxypeptidase activity; metal ion binding activity; and metallopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Mar 2025]

PIERCE1 Gene

piercer of microtubule wall 1

Predicted to be involved in axoneme assembly; establishment of left/right asymmetry; and flagellated sperm motility. Predicted to act upstream of or within DNA damage response; cellular response to UV-C; and regulation of gene expression. Located in axonemal microtubule. [provided by Alliance of Genome Resources, Mar 2025]

PIERCE2 Gene

piercer of microtubule wall 2

Predicted to be involved in axoneme assembly; determination of left/right symmetry; and flagellated sperm motility. Located in axonemal microtubule. [provided by Alliance of Genome Resources, Mar 2025]

MATCAP1 Gene

microtubule associated tyrosine carboxypeptidase 1

Enables tubulin-tyrosine carboxypeptidase. Predicted to be involved in brain development. Is active in microtubule. [provided by Alliance of Genome Resources, Mar 2025]

CIMAP1B Gene

ciliary microtubule associated protein 1B

Predicted to be located in motile cilium. Predicted to be active in cytoskeleton. [provided by Alliance of Genome Resources, Mar 2025]

SPMIP3 Gene

sperm microtubule inner protein 3

CIMAP3 Gene

ciliary microtubule associated protein 3

Enables cytoskeletal protein binding activity and enzyme binding activity. Involved in positive regulation of kinase activity. Predicted to be located in ciliary basal body and trans-Golgi network. [provided by Alliance of Genome Resources, Mar 2025]

CIMIP3 Gene

ciliary microtubule inner protein 3

Predicted to enable calcium ion binding activity. Predicted to be involved in visual perception. [provided by Alliance of Genome Resources, Mar 2025]

SPMIP8 Gene

sperm microtubule inner protein 8

Predicted to be involved in flagellated sperm motility. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. [provided by Alliance of Genome Resources, Mar 2025]

CIMAP1C Gene

ciliary microtubule associated protein 1C

Predicted to be active in cytoskeleton. [provided by Alliance of Genome Resources, Mar 2025]

CIMIP7 Gene

ciliary microtubule inner protein 7

SPMAP2 Gene

sperm microtubule associated protein 2

This gene is specifically expressed in the nucleus of haploid male germ cells. The orthologous gene in mice encodes a protein that may play a role in protein assembly through interactions with T-complex protein 1 subunit epsilon. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

CIMIP2C Gene

ciliary microtubule inner protein 2C

Predicted to be involved in flagellated sperm motility. Located in axonemal microtubule. [provided by Alliance of Genome Resources, Mar 2025]

CIMIP4 Gene

ciliary microtubule inner protein 4

Predicted to be located in sperm flagellum. [provided by Alliance of Genome Resources, Mar 2025]

CIMIP2A Gene

ciliary microtubule inner protein 2A

Predicted to be involved in flagellated sperm motility. Located in ciliary basal body. [provided by Alliance of Genome Resources, Mar 2025]

SPMIP6 Gene

sperm microtubule inner protein 6

This gene encodes a nuclear- or perinuclear-localized protein with no predicted domains or similarity to other known proteins. Expression of this gene is induced during the differentiation of bronchial epithelial cells, and the encoded protein may play a role in ciliogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

CIMIP1 Gene

ciliary microtubule inner protein 1

Located in cilium. [provided by Alliance of Genome Resources, Mar 2025]

CIMAP1A Gene

ciliary microtubule associated protein 1A

ODF3 is a component of sperm flagella outer dense fibers, which add stiffness, elastic recoil, and protection against shearing forces during sperm movement.[supplied by OMIM, Apr 2004]

SPMIP2 Gene

sperm microtubule inner protein 2

SPMIP9 Gene

sperm microtubule inner protein 9

Predicted to be involved in flagellated sperm motility. Located in cytosol. [provided by Alliance of Genome Resources, Mar 2025]

SPMIP7 Gene

sperm microtubule inner protein 7

Predicted to be involved in spermatogenesis. [provided by Alliance of Genome Resources, Mar 2025]

SPMIP5 Gene

sperm microtubule inner protein 5

Predicted to be involved in flagellated sperm motility. Predicted to be located in several cellular components, including cytoskeleton; motile cilium; and nucleus. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. [provided by Alliance of Genome Resources, Mar 2025]

CIMAP2 Gene

ciliary microtubule associated protein 2

SPMIP10 Gene

sperm microtubule inner protein 10

Predicted to be involved in flagellated sperm motility. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Predicted to be active in axonemal B tubule inner sheath and sperm flagellum. [provided by Alliance of Genome Resources, Mar 2025]

SPMIP1 Gene

sperm microtubule inner protein 1

SPMIP11 Gene

sperm microtubule inner protein 11

Predicted to be involved in flagellated sperm motility. Predicted to be located in cytoplasm; cytoskeleton; and sperm flagellum. Predicted to be active in axonemal A tubule inner sheath. [provided by Alliance of Genome Resources, Mar 2025]

CIMIP2B Gene

ciliary microtubule inner protein 2B

Predicted to be involved in flagellated sperm motility. Located in axonemal microtubule. [provided by Alliance of Genome Resources, Mar 2025]

SPMAP2L Gene

sperm microtubule associated protein 2 like

SPMIP4 Gene

sperm microtubule inner protein 4

SPMAP1 Gene

sperm microtubule associated protein 1

MNMIP1 Gene

manchette microtubule inner protein 1

Predicted to be involved in actin filament organization and cell migration. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]