Name

YAP1 Gene

Yes-associated protein 1

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]

BL5772 (YAP1) Gene Set

From NURSA Protein Complexes

proteins in the BL5772 (YAP1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

PMC7397849-supp_gad.338681.120_Supplemental_Table_S2.xlsx-S2B_in_vivo_shared-Suppl_Table_S2B_shared_genes_between_RCAS-YAP1-MAMLD1-dR3R1_RCAS-YAP1-FAM118B_RCAS-YAP1-TFE3_in_vivo_tumors_RCAS_mouse_TFE3 Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC7397849-supp_gad.338681.120_Supplemental_Table_S2.xlsx-S2B_in_vivo_shared-Suppl_Table_S2B_shared_genes_between_RCAS-YAP1-MAMLD1-dR3R1_RCAS-YAP1-FAM118B_RCAS-YAP1-TFE3_in_vivo_tumors_RCAS_mouse_TFE3 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

YAP1-20516196-MESC-MOUSE Gene Set

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the YAP1-20516196-MESC-MOUSE transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

YAP1 Gene Set

From ChEA Transcription Factor Targets

target genes of the YAP1 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

yap1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term yap1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

YAP1 Gene Set

From MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations

genes differentially expressed following the YAP1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.

YAP1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for YAP1 from the Pathway Commons Protein-Protein Interactions dataset.

YAP1- and WWTR1 (TAZ)-stimulated gene expression Gene Set

From Reactome Pathways 2014

proteins participating in the YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway from the Reactome Pathways dataset.

YAP1-20516196-MESCS-MOUSE Gene Set

From ChEA Transcription Factor Targets 2022

target genes of the YAP1-20516196-MESCS-MOUSE transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

YAP1 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the YAP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

miR 509 3p alteration of YAP1 ECM axis Gene Set

From WikiPathways Pathways 2024

proteins participating in the miR 509 3p alteration of YAP1 ECM axis pathway from the WikiPathways Pathways 2024 dataset.

RUNX3 regulates YAP1-mediated transcription Gene Set

From Reactome Pathways 2024

proteins participating in the RUNX3 regulates YAP1-mediated transcription pathway from the Reactome Pathways 2024 dataset.

YAP1- and WWTR1 (TAZ)-stimulated gene expression Gene Set

From Reactome Pathways 2024

proteins participating in the YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway from the Reactome Pathways 2024 dataset.

Supratentorial ependymoma, YAP1 fusion–positive Gene Set

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occuring with the disease Supratentorial ependymoma, YAP1 fusion–positive in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

YAP1 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the YAP1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.