Harmonizome 3.0

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cftr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for CFTR from the Pathway Commons Protein-Protein Interactions dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the CFTR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From Biocarta Pathways

proteins participating in the cystic fibrosis transmembrane conductance regulator (cftr) and beta 2 adrenergic receptor (b2ar) pathway pathway from the Biocarta Pathways dataset.

From CORUM Protein Complexes

proteins in the C-CFTR-NHERF(PDZ1 domain)-ezrin complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the (C-CFTR)2-NHERF-ezrin complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the C-CFTR-NHERF(PDZ2 domain)-ezrin complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the CFTR-NHERF-beta(2)AR signaling complex protein complex from the CORUM Protein Complexes dataset.

From GAD Gene-Disease Associations

genes associated with the disease cftr mutation spectrum in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GO Biological Process Annotations 2015

genes participating in the golgi to plasma membrane cftr protein transport biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of golgi to plasma membrane cftr protein transport biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of golgi to plasma membrane cftr protein transport biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the cytoplasmic sequestering of cftr protein biological process from the curated GO Biological Process Annotations 2015 dataset.

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the CFTR_inh-172 ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the CFTR regulator domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From HuBMAP Azimuth Cell Type Annotations

genes associated with the Human - Motor Cortex - Cluster - FEZF2+ CFTR+ Layer 5-6 glutamatergic neuron cell type from the HuBMAP Azimuth Cell Type Annotations dataset.

From Reactome Pathways 2024

proteins participating in the Defective CFTR causes cystic fibrosis pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RHO GTPases regulate CFTR trafficking pathway from the Reactome Pathways 2024 dataset.

From HuBMAP ASCT+B Annotations

biomarker genes for the Brain_CT2_Exc L5-6 FEZF2 CFTR cell type from the HuBMAP ASCT+B dataset.

From HuBMAP ASCT+B Augmented with RNA-seq Coexpression

biomarker genes for the Brain_CT2_Exc L5-6 FEZF2 CFTR cell type from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Congenital bilateral aplasia of vas deferens from CFTR mutation phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.