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Results for "FLT3": 1 gene, 40 gene sets

Name

FLT3 Gene

fms-related tyrosine kinase 3

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]

flt3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term flt3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

FLT3 Gene Set

From KEA Substrates of Kinases

substrates of the kinase FLT3 from the curated KEA Substrates of Kinases dataset.

FLT3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for FLT3 from the Pathway Commons Protein-Protein Interactions dataset.

FLT3 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase FLT3 from the curated PhosphoSitePlus Substrates of Kinases dataset.

FLT3 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the FLT3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

FLT3 Gene Set

From Kinase Library Tyrosine Kinome Atlas

substrates of the kinase FLT3 from the Kinase Library Tyrosine Kinome Atlas dataset.

Flt3 ligand Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Flt3 ligand protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Receptor-type tyrosine-protein kinase FLT3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Receptor-type tyrosine-protein kinase FLT3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

FLT3 p Gln640SerfsTer8 signaling Gene Set

From WikiPathways Pathways 2024

proteins participating in the FLT3 p Gln640SerfsTer8 signaling pathway from the WikiPathways Pathways 2024 dataset.

Drug resistance of FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

FLT3 Signaling Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 Signaling pathway from the Reactome Pathways 2024 dataset.

FLT3 mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

FLT3 signaling by CBL mutants Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 signaling by CBL mutants pathway from the Reactome Pathways 2024 dataset.

FLT3 signaling in disease Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 signaling in disease pathway from the Reactome Pathways 2024 dataset.

FLT3 signaling through SRC family kinases Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 signaling through SRC family kinases pathway from the Reactome Pathways 2024 dataset.

KW2449-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the KW2449-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

Negative regulation of FLT3 Gene Set

From Reactome Pathways 2024

proteins participating in the Negative regulation of FLT3 pathway from the Reactome Pathways 2024 dataset.

STAT5 activation downstream of FLT3 ITD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the STAT5 activation downstream of FLT3 ITD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by FLT3 ITD and TKD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FLT3 ITD and TKD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by FLT3 fusion proteins Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FLT3 fusion proteins pathway from the Reactome Pathways 2024 dataset.

crenolanib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the crenolanib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

gilteritinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the gilteritinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

lestaurtinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the lestaurtinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

linifanib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the linifanib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

midostaurin-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the midostaurin-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

pexidartinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the pexidartinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

ponatinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the ponatinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

quizartinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the quizartinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

semaxanib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the semaxanib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

sorafenib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the sorafenib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

sunitinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the sunitinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

tamatinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the tamatinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

tandutinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the tandutinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

RECOMBINANT FLT3 LIGAND Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the RECOMBINANT FLT3 LIGAND drug from theDGIdb Drug Targets 2026 dataset.

ANTI-FLT3/CD3 BISPECIFIC ANTIBODY CLN-049 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the ANTI-FLT3/CD3 BISPECIFIC ANTIBODY CLN-049 drug from theDGIdb Drug Targets 2026 dataset.

FLT3 INHIBITOR BMF-500 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3 INHIBITOR BMF-500 drug from theDGIdb Drug Targets 2026 dataset.

FLT3 INHIBITOR FF-10101 SUCCINATE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3 INHIBITOR FF-10101 SUCCINATE drug from theDGIdb Drug Targets 2026 dataset.

FLT3 TYROSINE KINASE INHIBITOR TTT-3002 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3 TYROSINE KINASE INHIBITOR TTT-3002 drug from theDGIdb Drug Targets 2026 dataset.

FLT3/ABL/AURORA KINASE INHIBITOR KW-2449 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3/ABL/AURORA KINASE INHIBITOR KW-2449 drug from theDGIdb Drug Targets 2026 dataset.

FLT3/CDK4/6 INHIBITOR FLX925 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3/CDK4/6 INHIBITOR FLX925 drug from theDGIdb Drug Targets 2026 dataset.